دورية أكاديمية
Synthesis, Characterization and Pharmacological Activities of 3,6-Disubstituted-1,2,4-triazolo [3,4-b]-1,3,4-thiadiazoles and their Dihydro Analogues
| العنوان: | Synthesis, Characterization and Pharmacological Activities of 3,6-Disubstituted-1,2,4-triazolo [3,4-b]-1,3,4-thiadiazoles and their Dihydro Analogues |
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| المؤلفون: | Vinod Mathew, J. Keshavayya, V. P. Vaidya |
| المصدر: | E-Journal of Chemistry, Vol 4, Iss 3, Pp 320-342 (2007) |
| بيانات النشر: | Wiley, 2007. |
| سنة النشر: | 2007 |
| المجموعة: | LCC:Chemistry |
| مصطلحات موضوعية: | Chemistry, QD1-999 |
| الوصف: | 4-Amino-5-aryl/heteroaryl substituted-3-mercapto-1,2,4-triazoles 3(a-d) were prepared from the corresponding aromatic carboxylic acids through a multi-step sequence. Compounds 3(a-d) were made to react with various aromatic/hetero aromatic acids and hetero aromatic aldehydes to give 3,6-disubstituted-1,2,4-triazolo [3,4-b]-1,3,4-thiadizoles and 3,6-disubstituted-5,6-dihydro-1,2,4-triazolo [3,4-b]-1,3,4-thiadizoles respectively. Elemental analysis, IR, 1H NMR and mass spectral data elucidated the structures of all newly synthesized compounds. Synthesized compounds are studied for their antibacterial, antifungal, anti-inflammatory and analgesic activities. Some of the tested compounds showed significant pharmacological activities. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 0973-4945 2090-9810 |
| Relation: | https://doaj.org/toc/0973-4945; https://doaj.org/toc/2090-9810 |
| DOI: | 10.1155/2007/605058 |
| URL الوصول: | https://doaj.org/article/546114aaafb04c91b17f3bf926829fab |
| رقم الأكسشن: | edsdoj.546114aaafb04c91b17f3bf926829fab |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 09734945 20909810 |
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| DOI: | 10.1155/2007/605058 |