دورية أكاديمية
Comparative Study on the Duration and Efficacy of Various Botulinum Toxin Type A Injections for Reducing Masseteric Muscle Bite Force and Treating Facial Wrinkles
| العنوان: | Comparative Study on the Duration and Efficacy of Various Botulinum Toxin Type A Injections for Reducing Masseteric Muscle Bite Force and Treating Facial Wrinkles |
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| المؤلفون: | Surachet Sirisuthivoranunt, Supisara Wongdama, Phumithep Phumariyapong, Ya-Nin Nokdhes, Panwadee Thongjaroensirikul, Thanya Techapichetvanich, Mattias Pettersson, Martin Ågren, Rungsima Wanitphakdeedecha |
| المصدر: | Dermatology and Therapy, Vol 14, Iss 5, Pp 1315-1325 (2024) |
| بيانات النشر: | Adis, Springer Healthcare, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Dermatology |
| مصطلحات موضوعية: | Botulinum toxin type A, Bite force, Wrinkles, Dermatology, RL1-803 |
| الوصف: | Abstract Objective Botulinum toxin serotype A (BoNT/A) is widely used for minimal invasive aesthetic treatments. Different brands of BoNT/A exhibit structural variations. The aim of this study was to compare the duration and efficacy of various BoNT/A brands available in Thailand for reducing bite force and treating wrinkles. Methods Fifty participants were randomly assigned to one of five groups, with each group receiving a different BoNT/A brand, namely, incobotulinumtoxinA (IncoA), onabotulinumtoxinA (OnaA), abobotulinumtoxinA (AboA), letibotulinumtoxinA (LetiA), and prabotulinumtoxinA (PraboA). BoNT/A was administered to the masseter muscle and the upper face. Bite force was measured before injection and at 2, 4, 8, 12, 16, 20, and 24 weeks post-injection. Evaluation scores for wrinkle improvement were assessed after the treatment. Results The most significant reduction in bite force occurred between 2 and 4 weeks post-injection. PraboA demonstrated the most substantial reduction in bite force, while IncoA had the least effect. However, the percentage of bite force reduction did not exhibit statistical significance between BoNT/A types. Additionally, the reduction in bite force for all BoNT/A types was reversed at 4 months post-injection. More than half of the participants experienced improvement beyond 16 weeks. Conclusions The structural differences among BoNT/A brands did not significantly affect the longevity and efficacy of bite force reduction and wrinkle treatment. Trial Registration ClinicalTrials.gov identifier: TCTR20211205001 (registered 4 Dec 2021). |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2193-8210 2190-9172 |
| Relation: | https://doaj.org/toc/2193-8210; https://doaj.org/toc/2190-9172 |
| DOI: | 10.1007/s13555-024-01177-1 |
| URL الوصول: | https://doaj.org/article/548766adb31e4f4ba5a0734982bfa552 |
| رقم الأكسشن: | edsdoj.548766adb31e4f4ba5a0734982bfa552 |
| قاعدة البيانات: | Directory of Open Access Journals |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 21938210 21909172 |
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| DOI: | 10.1007/s13555-024-01177-1 |