دورية أكاديمية
Features of the course and eradication of multidrug-resistant Pseudomonas aeruginosa infection in cystic fibrosis: clinical case
العنوان: | Features of the course and eradication of multidrug-resistant Pseudomonas aeruginosa infection in cystic fibrosis: clinical case |
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المؤلفون: | E. I. Kondratyeva, E. V. Loshkova, E. D. Nikolaeva, M. M. Khachiyan, G. N. Yankina |
المصدر: | Медицинский совет, Vol 0, Iss 16, Pp 166-173 (2021) |
بيانات النشر: | Remedium Group LLC, 2021. |
سنة النشر: | 2021 |
المجموعة: | LCC:Medicine |
مصطلحات موضوعية: | cystic fibrosis, pseudomonas aeruginosa, inhaled antibiotics, pulmonary exacerbations, nutritional status, vitamin d deficiency, Medicine |
الوصف: | Chronic lung infection caused by Pseudomonas aeruginosa reduces respiratory function and life expectancy in people with cystic fibrosis. Up to 2/3 of hospitalized patients, have antibiotic-resistant strains of Pseudomonas aeruginosa, which presents significant difficulties in prescribing eradication antibiotic therapy, which in some cases is aggravated by undesirable side effects of antimicrobial chemotherapy. The nutritional status of patients with cystic fibrosis is directly related to the activity of chronic pulmonary infection and the frequency of pulmonary exacerbations. A clinical example discusses the tactics of prescribing an alternative inhaled antibiotic aztreonam lysine (Cayston (Aztreonam lysine), Gilead Sciences Inc.) active against carbapenemases, including metallobetalactamases, in a patient with multidrug-resistant Pseudomonas aeruginosa. The clinical case demonstrates the successful eradication of the multidrug-resistant biotypes of Pseudomonas aeruginosa, and, as a consequence, the improvement of respiratory function and nutritional status, including the normalization of the 25(OH)D level in the patient. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | Russian |
تدمد: | 2079-701X 2658-5790 |
Relation: | https://www.med-sovet.pro/jour/article/view/6475; https://doaj.org/toc/2079-701X; https://doaj.org/toc/2658-5790 |
DOI: | 10.21518/2079-701X-2021-16-166-173 |
URL الوصول: | https://doaj.org/article/54ba31e6458c4029b2b8a96b2edb2969 |
رقم الأكسشن: | edsdoj.54ba31e6458c4029b2b8a96b2edb2969 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 2079701X 26585790 |
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DOI: | 10.21518/2079-701X-2021-16-166-173 |