دورية أكاديمية
On the interchangeability of calcineurine inhibitors
| العنوان: | On the interchangeability of calcineurine inhibitors |
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| المؤلفون: | K. E. Zatolochina, R. N. Alyautdin, E. O. Zhuravleva, E. Yu. Pasternak, M. A. Darmostukova, E. Yu. Kolesnikova, B. K. Romanov |
| المصدر: | Безопасность и риск фармакотерапии, Vol 0, Iss 2, Pp 5-10 (2018) |
| بيانات النشر: | Ministry of Health of the Russian Federation, Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products», 2018. |
| سنة النشر: | 2018 |
| المجموعة: | LCC:Therapeutics. Pharmacology |
| مصطلحات موضوعية: | ингибиторы кальциневрина, циклоспорин, такролимус, биоэквивалентность, взаимозаменяемость, calcineurine inhibitors, cyclosporine, tacrolimus, bioequivalence, interchangeability, Therapeutics. Pharmacology, RM1-950 |
| الوصف: | Calcineurin inhibitors, cyclosporine and tacrolimus, are the main immunosuppressants used in solid organ transplantation, but the peculiarities of their pharmacokinetics allow to classify them to a group of medicines with a narrow therapeutic range. Currently in Russia more than 10 generic drugs of cyclosporine and tacrolimus are used. In this review the problem of interchangeability of cyclosporine and tacrolimus is discussed. The pharmacokinetic and technological factors that affect the bioequivalence of calcineurin inhibitors are presented. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | Russian |
| تدمد: | 2312-7821 2619-1164 |
| Relation: | https://www.risksafety.ru/jour/article/view/41; https://doaj.org/toc/2312-7821; https://doaj.org/toc/2619-1164 |
| URL الوصول: | https://doaj.org/article/5530f2035b564d63ab942c4f4257a11f |
| رقم الأكسشن: | edsdoj.5530f2035b564d63ab942c4f4257a11f |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 23127821 26191164 |
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