دورية أكاديمية

Apparent bias toward long gene misregulation in MeCP2 syndromes disappears after controlling for baseline variations

التفاصيل البيبلوغرافية
العنوان: Apparent bias toward long gene misregulation in MeCP2 syndromes disappears after controlling for baseline variations
المؤلفون: Ayush T. Raman, Amy E. Pohodich, Ying-Wooi Wan, Hari Krishna Yalamanchili, William E. Lowry, Huda Y. Zoghbi, Zhandong Liu
المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
بيانات النشر: Nature Portfolio, 2018.
سنة النشر: 2018
المجموعة: LCC:Science
مصطلحات موضوعية: Science
الوصف: Recent studies have suggested that long genes (>100 kb) are more likely to be misregulated in some neurological diseases, such as autism and Rett syndrome. Here the authors find that the apparent length-dependent trends previously observed in MeCP2 microarray and RNA-sequencing datasets disappeared after controlling for baseline variations.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2041-1723
Relation: https://doaj.org/toc/2041-1723
DOI: 10.1038/s41467-018-05627-1
URL الوصول: https://doaj.org/article/558d10a20c1240ebb849e9756a465fe5
رقم الأكسشن: edsdoj.558d10a20c1240ebb849e9756a465fe5
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:20411723
DOI:10.1038/s41467-018-05627-1