دورية أكاديمية
Apparent bias toward long gene misregulation in MeCP2 syndromes disappears after controlling for baseline variations
العنوان: | Apparent bias toward long gene misregulation in MeCP2 syndromes disappears after controlling for baseline variations |
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المؤلفون: | Ayush T. Raman, Amy E. Pohodich, Ying-Wooi Wan, Hari Krishna Yalamanchili, William E. Lowry, Huda Y. Zoghbi, Zhandong Liu |
المصدر: | Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018) |
بيانات النشر: | Nature Portfolio, 2018. |
سنة النشر: | 2018 |
المجموعة: | LCC:Science |
مصطلحات موضوعية: | Science |
الوصف: | Recent studies have suggested that long genes (>100 kb) are more likely to be misregulated in some neurological diseases, such as autism and Rett syndrome. Here the authors find that the apparent length-dependent trends previously observed in MeCP2 microarray and RNA-sequencing datasets disappeared after controlling for baseline variations. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 2041-1723 |
Relation: | https://doaj.org/toc/2041-1723 |
DOI: | 10.1038/s41467-018-05627-1 |
URL الوصول: | https://doaj.org/article/558d10a20c1240ebb849e9756a465fe5 |
رقم الأكسشن: | edsdoj.558d10a20c1240ebb849e9756a465fe5 |
قاعدة البيانات: | Directory of Open Access Journals |
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