دورية أكاديمية
Possible Role of Serum Leptin as Biomarker in COPD
العنوان: | Possible Role of Serum Leptin as Biomarker in COPD |
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المؤلفون: | Yanitsa A. Zhelyazkova, Tanya T. Tacheva, Dimo M. Dimov, Denitsa G. Vlaykova, Aneliya V. Bivolarska, Tatyana I. Vlaykova |
المصدر: | Folia Medica, Vol 61, Iss 4, Pp 512-521 (2019) |
بيانات النشر: | Pensoft Publishers, 2019. |
سنة النشر: | 2019 |
المجموعة: | LCC:Medicine |
مصطلحات موضوعية: | biomarker, COPD, ELISA, leptin, Medicine |
الوصف: | Leptin is one of the adipokines shown to exert a significant effect in respiratory diseases, including chronic obstructive pulmonary disease (COPD).The aim of the present study was to evaluate the possible role of serum leptin as biomarker in COPD.The serum leptin levels were assessed in 58 patents with stable COPD and 21 controls applying ELISA method.The leptin levels were higher, although not significantly, in COPD patients than in controls (221.52±24.28(SE) vs. 165.04±26.01 pg/ml, p=0.197). This tendency turned out significant when only females were compared (414.60±60.63 vs. 219.40±44.15 pg/ml, p=0.038). The levels of leptin were highly dependent on the BMI both in COPD patients (p |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 1314-2143 0204-8043 |
Relation: | https://foliamedica.bg/article/47745/download/pdf/; https://foliamedica.bg/article/47745/download/xml/; https://foliamedica.bg/article/47745/; https://doaj.org/toc/0204-8043; https://doaj.org/toc/1314-2143 |
DOI: | 10.3897/folmed.61.e47745 |
URL الوصول: | https://doaj.org/article/55da60f46c544a83a7964114373c1a18 |
رقم الأكسشن: | edsdoj.55da60f46c544a83a7964114373c1a18 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 13142143 02048043 |
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DOI: | 10.3897/folmed.61.e47745 |