دورية أكاديمية
Synergistic antimicrobial action of phyco-synthesized silver nanoparticles and nano-fungal chitosan composites against drug resistant bacterial pathogens
| العنوان: | Synergistic antimicrobial action of phyco-synthesized silver nanoparticles and nano-fungal chitosan composites against drug resistant bacterial pathogens |
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| المؤلفون: | Mohammed S. Alsaggaf, Ahmed A. Tayel, Mousa A. Alghuthaymi, Shaaban H. Moussa |
| المصدر: | Biotechnology & Biotechnological Equipment, Vol 34, Iss 1, Pp 631-639 (2020) |
| بيانات النشر: | Taylor & Francis Group, 2020. |
| سنة النشر: | 2020 |
| المجموعة: | LCC:Biotechnology |
| مصطلحات موضوعية: | antibacterial action, characterization, green synthesis, microbial chitosan, nanoconjugates, Biotechnology, TP248.13-248.65 |
| الوصف: | Here we report the phycosynthesis of silver nanoparticles (Ag-NPs), using Codium capitatum extract, and the synthesis of fungal chitosan nanoparticles (FC-NPs), using extracted chitosan from Aspergillus niger mycelia. Then nanoconjugates from FC/Ag-NPs were produced and evaluated. The synthesized NPs had mean particles’ size diameters of 37.2, 68.4 and 79.6 nm for Ag-NPs, FC-NPs and FC/Ag-NPs, respectively. The FTIR (Fourier-transform infrared spectroscopy) analysis of synthesized NPs indicated their cross-linkage and interaction. The antibacterial activity of each type of NPs was assayed against drug resistant pathogens of Salmonella Typhimurium and Staphylococcus aureus. All NPs had powerful inhibitory effect and FC/Ag nanoconjugates had stronger activity than the other types. Scanning micrographs of FC/Ag-NPs treated S. Typhimurium elucidated vigorous alterations in cell surfaces and lethal damage to bacterial structure after 8 h of treatment. The nanoconjugates form FC-NPs and Ag-NPs had minute particle size with increasing bioactivity as antimicrobial agents to control drug resistant bacterial pathogens, which recommends their further exploration for topical applications in biomedical sectors. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1310-2818 1314-3530 13102818 |
| Relation: | https://doaj.org/toc/1310-2818; https://doaj.org/toc/1314-3530 |
| DOI: | 10.1080/13102818.2020.1796787 |
| URL الوصول: | https://doaj.org/article/5620776f052e4618bc6b77aec4532cfe |
| رقم الأكسشن: | edsdoj.5620776f052e4618bc6b77aec4532cfe |
| قاعدة البيانات: | Directory of Open Access Journals |
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Full Text Finder | تدمد: | 13102818 13143530 |
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| DOI: | 10.1080/13102818.2020.1796787 |