دورية أكاديمية
أعرض في EDS

Significant Hyperfibrinolysis in a Patient With Intracardiac Thrombosis: To Give Antifibrinolytics or Not?

التفاصيل البيبلوغرافية
العنوان: Significant Hyperfibrinolysis in a Patient With Intracardiac Thrombosis: To Give Antifibrinolytics or Not?
المؤلفون: Eric R. Simon, MD, Christopher D. Darling, DO, Laura L. Hammel, MD
المصدر: Transplantation Direct, Vol 5, Iss 3, p e431 (2019)
بيانات النشر: Wolters Kluwer, 2019.
سنة النشر: 2019
المجموعة: LCC:Surgery
مصطلحات موضوعية: Surgery, RD1-811
الوصف: Abstract. The hemostatic system is a delicate balance between the coagulation, anticoagulation, and fibrinolytic systems and is responsible for preventing both hemorrhage and thrombosis. End stage liver disease is characterized by a rebalanced hemostatic system that is fragile and easily tipped towards either hemorrhage or thrombosis. During an orthotopic liver transplantation, patients are exposed to a wide variety of factors that can shift them from a hypercoagulable state to a hypocoagulable state almost instantaneously. The treatment for these two disease states contradict each other, and therefore patients in this condition can be extremely difficult to manage. Here, we present a patient who underwent an orthotopic liver transplantation and suffered an intracardiac thrombosis shortly after reperfusion of the donor graft, that resolved with supportive care, who then went on to develop severe persistent hyperfibrinolysis and massive hemorrhage that was successfully treated with an antifibrinolytic agent.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2373-8731
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Relation: http://journals.lww.com/transplantationdirect/fulltext/10.1097/TXD.0000000000000875; https://doaj.org/toc/2373-8731
DOI: 10.1097/TXD.0000000000000875
URL الوصول: https://doaj.org/article/56b603286dd94ec3969de01fb28e73b9
رقم الأكسشن: edsdoj.56b603286dd94ec3969de01fb28e73b9
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:23738731
00000000
DOI:10.1097/TXD.0000000000000875