دورية أكاديمية
Intra-Abdominal Desmoplastic Small Round Cell Tumor (DSRCT) and the Role of Hyperthermic Intraperitoneal Chemotherapy (HIPEC): A Review
العنوان: | Intra-Abdominal Desmoplastic Small Round Cell Tumor (DSRCT) and the Role of Hyperthermic Intraperitoneal Chemotherapy (HIPEC): A Review |
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المؤلفون: | Sophie J. M. Reijers, Caroline C. H. Siew, Niels F. M. Kok, Charles Honoré, Winan J. van Houdt |
المصدر: | Current Oncology, Vol 30, Iss 4, Pp 3951-3963 (2023) |
بيانات النشر: | MDPI AG, 2023. |
سنة النشر: | 2023 |
المجموعة: | LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
مصطلحات موضوعية: | DSRCT, desmoplastic small round cell tumor, CRS, cytoreductive surgery, HIPEC, hyperthermic intraperitoneal chemotherapy, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
الوصف: | Desmoplastic small round cell tumor is a very rare and highly aggressive soft tissue sarcoma, usually presenting with multiple intra-abdominal tumors in young males. Patients present with advanced disease and the overall survival is dismal. Multiple studies report relatively favorable outcomes with multimodal treatment consisting of chemotherapy, surgery and radiotherapy. If resection is feasible, complete cytoreductive surgery is the cornerstone of surgical treatment. The benefit of hyperthermic intraperitoneal chemotherapy in addition to cytoreductive surgery is unclear, and few studies have evaluated this option. We sought to identify the role of hyperthermic intraperitoneal chemotherapy in patients with intra-abdominal desmoplastic small round cell tumor. Our review of the available literature revealed no clear survival benefit in performing hyperthermic intraperitoneal chemotherapy after cytoreductive surgery. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 30040299 1718-7729 1198-0052 |
Relation: | https://www.mdpi.com/1718-7729/30/4/299; https://doaj.org/toc/1198-0052; https://doaj.org/toc/1718-7729 |
DOI: | 10.3390/curroncol30040299 |
URL الوصول: | https://doaj.org/article/56c9b91388c14da188db0adeb6c9c0c5 |
رقم الأكسشن: | edsdoj.56c9b91388c14da188db0adeb6c9c0c5 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 30040299 17187729 11980052 |
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DOI: | 10.3390/curroncol30040299 |