دورية أكاديمية
Evaluation of the neutralizing capacity of Androctonus crassicauda (Olivier, 1807) antivenom against Leiurus quinquestriatus (Ehrenberg, 1928) venom (Scorpiones: Buthidae)
| العنوان: | Evaluation of the neutralizing capacity of Androctonus crassicauda (Olivier, 1807) antivenom against Leiurus quinquestriatus (Ehrenberg, 1928) venom (Scorpiones: Buthidae) |
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| المؤلفون: | O Ozkan, S Adiguzel, B Inceoglu, J Lango, M Ertek, BD Hammock |
| المصدر: | Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 14, Iss 3, Pp 481-496 (2008) |
| بيانات النشر: | SciELO, 2008. |
| سنة النشر: | 2008 |
| المجموعة: | LCC:Arctic medicine. Tropical medicine LCC:Toxicology. Poisons LCC:Zoology |
| مصطلحات موضوعية: | scorpion, Androctonus crassicauda, Leiurus quinquestriatus, venom, monovalent antivenom, paraspecific activity, Arctic medicine. Tropical medicine, RC955-962, Toxicology. Poisons, RA1190-1270, Zoology, QL1-991 |
| الوصف: | The two most venomous species of the family Buthidae, Leiurus quinquestriatus and Androctonus crassicauda, are found in Africa and in the Middle East. Potency and paraspecific activities of A. crassicauda antivenom (RSHC anti-Ac) were tested against L. quinquestriatus venom. The sera produced by Refik Saydam Hygiene Center (RSHC) showed strong reactivity against the venoms of A. crassicauda and L. quinquestriatus in western blotting and dot-blot analysis. RSHC anti-Ac presents immunoactivity and neutralizing potential against Leiurus quinquestriatus venom. Neutralization capacity of antivenom was found to be 400 µL against 40 minimum lethal doses (MLD) of A. crassicauda scorpion venom and 10 MLD of L. quinquestriatus venom. This study indicates that the RSHC anti-Ac could be used for treating L. quinquestriatus stings. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1678-9199 |
| Relation: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992008000300008; https://doaj.org/toc/1678-9199 |
| DOI: | 10.1590/S1678-91992008000300008 |
| URL الوصول: | https://doaj.org/article/d572eea8ecf94f039723d70835c6fb76 |
| رقم الأكسشن: | edsdoj.572eea8ecf94f039723d70835c6fb76 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 16789199 |
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| DOI: | 10.1590/S1678-91992008000300008 |