دورية أكاديمية
Can clinical parameters at admission predict severity and intensive care unit mortality outcomes in patients with COVID-19?
| العنوان: | Can clinical parameters at admission predict severity and intensive care unit mortality outcomes in patients with COVID-19? |
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| المؤلفون: | K Fibi Ninan, Ramya Iyadurai, Justin K Varghese, J Jonathan Arul Jeevan, Karthik Gunasekaran, Reka Karuppusami, Binila Chacko, K Jacob Johnson, Amit Mandal, Nivin Stanley David |
| المصدر: | Current Medical Issues, Vol 21, Iss 3, Pp 168-173 (2023) |
| بيانات النشر: | Wolters Kluwer Medknow Publications, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Medicine |
| مصطلحات موضوعية: | acute respiratory distress syndrome, covid-19, prognostic factors, Medicine |
| الوصف: | Background: COVID-19 acute respiratory distress syndrome (ARDS) is associated with high morbidity and mortality. Identification of clinical prognostic factors at admission is crucial in the triage and therapeutic selection of patients in resource-poor settings. The study was done to identify clinical parameters at admission to prognosticate patients who required intensive care unit (ICU) admission. Methods: In this retrospective study, the clinical parameters and outcomes of critically ill patients admitted from a single medical unit during the second wave of COVID-19 were studied. Patients were categorized as survivors and nonsurvivors. Factors associated with mortality were explored using Fisher's exact and t-test as appropriate. Results: The study population included 62 patients with a male: female ratio of 43 (69.3%):19 (30.7%) with a mean (standard deviation [SD]) age of 50.97 (±9.9) years. The mean (SD) O2 saturation was 82% (±10%) and median (interquartile range) PaO2/FiO2 ratio was 161 (89–214) on arrival to the emergency department. Forty-two (66%) required mechanical ventilation and the mean (SD) duration of hospital stay was 20 (±15) days. Thirty-six patients died, and the overall mortality was 58.1%. Increasing age, low SpO2 at presentation to the hospital, and need for mechanical ventilation were noted to be independent predictors of mortality with an odds ratio of 5.1 (95% confidence interval) (1.61–16.2) (P = 0.006) and 25 (3.70–180.19) (P = 0.001), respectively. Admission respiratory rate >36/min (P = 0.009) and SpO2 ≤83% (P = 0.001) were predictive of increased mortality among ICU patients. Conclusion: Low SpO2 at presentation (36/min), and requirement of mechanical ventilation were strong predictors of mortality in patients admitted to ICU with COVID-19 ARDS. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 0973-4651 2666-4054 |
| Relation: | http://www.cmijournal.org/article.asp?issn=0973-4651;year=2023;volume=21;issue=3;spage=168;epage=173;aulast=Ninan; https://doaj.org/toc/0973-4651; https://doaj.org/toc/2666-4054 |
| DOI: | 10.4103/cmi.cmi_6_23 |
| URL الوصول: | https://doaj.org/article/ee57ca06d50246b8a1eddf8f752f1907 |
| رقم الأكسشن: | edsdoj.57ca06d50246b8a1eddf8f752f1907 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 09734651 26664054 |
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| DOI: | 10.4103/cmi.cmi_6_23 |