دورية أكاديمية
أعرض في EDS

Tannic Acid Coating Augments Glioblastoma Cellular Uptake of Magnetic Nanoparticles with Antioxidant Effects

التفاصيل البيبلوغرافية
العنوان: Tannic Acid Coating Augments Glioblastoma Cellular Uptake of Magnetic Nanoparticles with Antioxidant Effects
المؤلفون: Małgorzata Świętek, Yunn-Hwa Ma, Nian-Ping Wu, Aleksandra Paruzel, Waldemar Tokarz, Daniel Horák
المصدر: Nanomaterials, Vol 12, Iss 8, p 1310 (2022)
بيانات النشر: MDPI AG, 2022.
سنة النشر: 2022
المجموعة: LCC:Chemistry
مصطلحات موضوعية: tannic acid, magnetic nanoparticles, antioxidant activity, cellular uptake, Chemistry, QD1-999
الوصف: Coating of nanoparticles with gallates renders them antioxidant and enhances cellular internalization. In this study, (amino)silica magnetic particles modified with tannic acid (TA) and optionally with chitosan (CS) were developed, and their physicochemical properties and antioxidant activity were evaluated. The results demonstrated that the TA-modified aminosilica-coated particles, as well as the silica-coated particles with a double TA layer, exhibited high antioxidant activity, whereas the silica-coated particles with no or only a single TA layer were well-internalized by LN-229 cells. In addition, a magnet placed under the culture plates greatly increased the cellular uptake of all TA-coated magnetic nanoparticles. The coating thus had a considerable impact on nanoparticle–cell interactions and particle internalization. The TA-coated magnetic nanoparticles have great potential as intracellular carriers with preserved antioxidant activity.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 12081310
2079-4991
Relation: https://www.mdpi.com/2079-4991/12/8/1310; https://doaj.org/toc/2079-4991
DOI: 10.3390/nano12081310
URL الوصول: https://doaj.org/article/57ee7094da934e12b266d2a617950e6e
رقم الأكسشن: edsdoj.57ee7094da934e12b266d2a617950e6e
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:12081310
20794991
DOI:10.3390/nano12081310