دورية أكاديمية
Association between The Number of Retrieved Mature Oocytes and Insulin Resistance or Sensitivity in Infertile Women Polycystic Ovary Syndrome
| العنوان: | Association between The Number of Retrieved Mature Oocytes and Insulin Resistance or Sensitivity in Infertile Women Polycystic Ovary Syndrome |
|---|---|
| المؤلفون: | Fatemeh Hassani, Shahrbanoo Oryan, Masood Bazrgar, Ashraf Moini, Nahid Nasiri, Azadeh Ghaheri |
| المصدر: | International Journal of Fertility and Sterility, Vol 12, Iss 4, Pp 310-315 (2019) |
| بيانات النشر: | Royan Institute (ACECR), Tehran, 2019. |
| سنة النشر: | 2019 |
| المجموعة: | LCC:Medicine (General) |
| مصطلحات موضوعية: | assisted reproductive technology, insulin resistance, oocyte, polycystic ovary syndrome, Medicine (General), R5-920 |
| الوصف: | Background The objective of this study was to describe the association between luteinizing hormone (LH)/ follicle-stimulating hormone (FSH) ratio and demographic variables and maturation stage of oocytes in insulin- resistant and insulin-sensitive patients with polycystic ovary syndrome (PCOS) in comparison with control group. Materials and Methods In this case-control study, 60 patients with in vitro fertilization (IVF)/intracytoplas- mic sperm injection (ICSI) indication were subdivided into 3 groups as follow: 20 subjects were assigned to control (fertile women with male infertility history) group, 20 subjects with PCOS were insulin resistant (IR) and 20 subjects with PCOS were insulin sensitive (IS). After puncture, retrieved oocytes were classified into metaphase II (MII) as mature and in metaphase I (MI) or germinal vesicle stage (GV) as immature. Regres- sion analyses were used to explore the association between MII oocyte number and demographic and clinical variables. Results LH/FSH ratio was significantly higher in PCOS-IR women compared to controls but not significantly dif- ferent from that of PCOS-IS group. PCOS-IR women had lower MII oocyte number compared with that of controls. According to multiple regression analysis, the number of previous assisted reproductive technology (ART) cycles was negatively associated with the number of MII oocytes. Conclusion Insulin resistance can be associated with reductions in MII oocyte number in patients with PCOS. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2008-076X 2008-0778 |
| Relation: | http://www.ijfs.ir/article_45509_6ba1d701d08c57f12c63fd767d01e66f.pdf; https://doaj.org/toc/2008-076X; https://doaj.org/toc/2008-0778 |
| DOI: | 10.22074/ijfs.2019.5422 |
| URL الوصول: | https://doaj.org/article/57f56ce33b4b41a0972363528ca9c060 |
| رقم الأكسشن: | edsdoj.57f56ce33b4b41a0972363528ca9c060 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 2008076X 20080778 |
|---|---|
| DOI: | 10.22074/ijfs.2019.5422 |