دورية أكاديمية
Development of postcastration syndrome and corrective effect of xenon in exponential dose regimen in young patients with gynecological cancers
| العنوان: | Development of postcastration syndrome and corrective effect of xenon in exponential dose regimen in young patients with gynecological cancers |
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| المؤلفون: | O. I. Kit, N. N. Popova, A. I. Shikhlyarova, E. M. Frantsiyants, T. I. Moiseenko, A. P. Menshenina, G. V. Zhukova, T. P. Protasova, Yu. Yu. Arapova |
| المصدر: | Южно-Российский онкологический журнал, Vol 1, Iss 3, Pp 6-17 (2020) |
| بيانات النشر: | ANO "Perspective of oncology", 2020. |
| سنة النشر: | 2020 |
| المجموعة: | LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
| مصطلحات موضوعية: | рак шейки матки, рак молочной железы, посткастрационный синдром, ксенонотерапия, экспоненциальный режим дозирования, адаптационные реакции, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
| الوصف: | Purpose of the study. Investigation of possible optimization of treatment in patients with breast cancer and cervical cancer with low-dose xenon therapy.Patients and methods. The study included 156 patients with pT1В2N0M0 cervical cancer (CC) and pT2N1M0 breast cancer (BC) of the reproductive age (29–45 years) after radical treatment, including forced surgical castration in hormone-positive breast cancer with concomitant gynecological pathology. Since the formation of pathological syndromes, 1 cycle (5 sessions) of low-dose xenon inhalation therapy (XT) was performed, with an algorithm for xenon dose calculation and exposure according to the exponential pattern of decreasing concentration and increasing exposure, with an individual approach. Together with general clinical and laboratory examinations, we used international scales for assessing the severity of the patient condition by the Kupperman menopausal index (MMI), ESAS, quality of life (MOS-SF-36), in a modification of the Russian International Center, pain (VAS); the types of general adaptive reactions were identified by the method of L.Kh. Garkavi.Results. Important advantages of a new method associated with a rapid regression of pathological psychosomatic symptoms were revealed after XT. MMI values (p |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | Russian |
| تدمد: | 2686-9039 2687-0533 |
| Relation: | https://www.cancersp.com/jour/article/view/69; https://doaj.org/toc/2686-9039 |
| DOI: | 10.37748/2687-0533-2020-1-3-1 |
| URL الوصول: | https://doaj.org/article/5827018f8f794714acb48a7fb0cd2ba6 |
| رقم الأكسشن: | edsdoj.5827018f8f794714acb48a7fb0cd2ba6 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 26869039 26870533 |
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| DOI: | 10.37748/2687-0533-2020-1-3-1 |