دورية أكاديمية

Varied dose exposures to ultrafine particles in the motorcycle smoke cause kidney cell damages in male mice

التفاصيل البيبلوغرافية
العنوان: Varied dose exposures to ultrafine particles in the motorcycle smoke cause kidney cell damages in male mice
المؤلفون: Arinto Y.P. Wardoyo, Unggul P. Juswono, Johan A.E. Noor
المصدر: Toxicology Reports, Vol 5, Iss , Pp 383-389 (2018)
بيانات النشر: Elsevier, 2018.
سنة النشر: 2018
المجموعة: LCC:Toxicology. Poisons
مصطلحات موضوعية: Toxicology. Poisons, RA1190-1270
الوصف: Ultrafine particles (UFPs) are one of motorcycle exhaust emissions which can penetrate the lung alveoli and deposit in the kidney. This study was aimed to investigate mice kidney cell physical damage (deformation) due to motorcycle exhaust emission exposures. The motorcycle exhaust emissions were sucked from the muffler with the rate of 33 cm3/s and passed through an ultrafine particle filter system before introduced into the mice exposure chamber. The dose concentration of the exhaust emissions was varied by setting the injected time of the 20s, 40s, 60s, 80s, and 100s. The mice were exposed to the smoke in the chamber for 100 s twice a day. The impact of the ultrafine particles on the kidney was observed by identifying the histological image of the kidney cell deformation using a microscope. The exposure was conducted for 10 days. The kidney observations were carried out on day 11. The results showed that there was a significant linear correlation between the total concentration of ultrafine particles deposited in the kidneys and the physical damage percentages. The increased concentrations of ultrafine particles caused larger cell deformation to the kidneys. Keywords: Ultrafine particles exposure, Motorcycle exhaust emission, Mice, Kidney cell damages
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2214-7500
Relation: http://www.sciencedirect.com/science/article/pii/S2214750018301203; https://doaj.org/toc/2214-7500
DOI: 10.1016/j.toxrep.2018.02.014
URL الوصول: https://doaj.org/article/d58757a310b84946a12342c6ad98af3e
رقم الأكسشن: edsdoj.58757a310b84946a12342c6ad98af3e
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:22147500
DOI:10.1016/j.toxrep.2018.02.014