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Exploring the potential of a newly developed pectin-chitosan polyelectrolyte composite on the surface of commercially pure titanium for dental implants

التفاصيل البيبلوغرافية
العنوان: Exploring the potential of a newly developed pectin-chitosan polyelectrolyte composite on the surface of commercially pure titanium for dental implants
المؤلفون: Mohammed Husssein M. Alsharbaty, Ghassan A. Naji, Sameh S. Ali
المصدر: Scientific Reports, Vol 13, Iss 1, Pp 1-18 (2023)
بيانات النشر: Nature Portfolio, 2023.
سنة النشر: 2023
المجموعة: LCC:Medicine
LCC:Science
مصطلحات موضوعية: Medicine, Science
الوصف: Abstract Pectin and chitosan are natural polysaccharides obtained from fruit peels and exoskeletons of crustaceans and insects. They are safe for usage in food products and are renewable and biocompatible. They have further applications as wound dressings, body fat reduction, tissue engineering, and auxiliary agents in drug delivery systems. The healing process is usually long and painful. Adding a new material such as a pectin-chitosan composite to the implant surface or body would create unique biological responses to accelerate healing and delivery of target-specific medication at the implant site. The present study utilized the electrospraying process to create pectin-chitosan polyelectrolyte composite (PCPC) coatings with various ratios of 1:1, 2:1, 1:2, 1:3, and 3:1 on commercially pure titanium substrates. By means of FESEM, AFM, wettability, cross-cut adhesion, and microhardness were assessed the PCPC coatings’ physical and mechanical properties. Subsequently, the antibacterial properties of the coating composite were assessed. AFM analysis revealed higher surface roughness for group 5 and homogenous coating for group 1. Group 3 showed the lowest water contact angle of 66.7° and all PCPC coatings had significantly higher Vickers hardness values compared to the control uncoated CpTi samples. Groups 3 and 4 showed the best adhesion of the PCPC to the titanium substrates. Groups 3, 4, and 5 showed antibacterial properties with a high zone of inhibitions compared to the control. The PCPC coating's characteristics can be significantly impacted by using certain pectin-chitosan ratios. Groups 3 (1:2) and 4 (1:3) showed remarkable morphological and mechanical properties with better surface roughness, greater surface strength, improved hydrophilicity, improved adhesion to the substrate surface, and additionally demonstrated significant antibacterial properties. According to the accomplished in vitro study outcomes, these particular PCPC ratios can be considered as an efficient coating for titanium dental implants.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2045-2322
Relation: https://doaj.org/toc/2045-2322
DOI: 10.1038/s41598-023-48863-2
URL الوصول: https://doaj.org/article/593fb28d582e4ab3b06b1c2c76a39416
رقم الأكسشن: edsdoj.593fb28d582e4ab3b06b1c2c76a39416
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:20452322
DOI:10.1038/s41598-023-48863-2