دورية أكاديمية

HUMAN GRANULOCYTOTROPIC ANAPLASMOSIS

التفاصيل البيبلوغرافية
العنوان: HUMAN GRANULOCYTOTROPIC ANAPLASMOSIS
المؤلفون: Y A Klimova, N A Polovinkina, V V Konnov, D S Konnov
المصدر: RUDN Journal of Medicine, Vol 22, Iss 3, Pp 322-331 (2018)
بيانات النشر: Peoples’ Friendship University of Russia (RUDN University), 2018.
سنة النشر: 2018
المجموعة: LCC:Medicine
مصطلحات موضوعية: Human granulocytotropic anaplasmosis, HGA, Anaplasma phagocytophilum, symptoms, diagnosis, Medicine
الوصف: Natural focal tick-borne infections are widespread in the world and are characterized by a great etiologic diversity. Human granulocytotropic anaplasmosis (HGA), also transmitted by the bite of ticks became relevant in the last century of detection not only in animals but also in humans. The review provides an overview of the incidence of HGA in Russia and in the world, the prevalence of the habitat of mites, the diversity of reservoirs and sources of infection, mechanisms and pathways of transmission of the pathogen Anaplasma phagocytophilum and its biological features. The links and stages of the disease pathogenesis are considered in detail. Scientific data on the clinical course of the disease, the frequency and diversity of various symptoms of the disease, the issues of laboratory and differential diagnosis of anaplasmosis and its place in the nosological structure in patients with fever of unknown origin are discussed. At the same time, choosing a method of laboratory diagnostics it is necessary to take into account that molecular-genetic method (polymerase chain reaction PCR-diagnosis) allows to confirm the diagnosis quickly, while serological methods of research in a greater degree - to put a retrospective diagnosis. The article presents current data on the treatment of disease and methods of HGA prevention and also presents the results of the authors’ own observations based on the survey of 63 patients. The analysis of Moscow residents treatment about sucking mites is carried out and summarized the incidence of infections transmitted by ixode mites. For the diagnosis of HGA and other tick-borne fever used a technique called polymerase chain reaction. It has been revealed that in Moscow, lime borreliosis occupies a leading place among mites associated with infections 60%, and the share of granulocytic anaplasmosis of a person is only 5% of patients. However, the study of ticks for the presence of HGA pathogens and other natural focal tick infections is carried out in insufficient volume (less than 30%), which should be considered in clinical and laboratory differential diagnosis, as well as preventive measures.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
Russian
تدمد: 2313-0245
2313-0261
Relation: http://journals.rudn.ru/medicine/article/viewFile/19692/16311; https://doaj.org/toc/2313-0245; https://doaj.org/toc/2313-0261
DOI: 10.22363/2313-0245-2018-22-3-322-331
URL الوصول: https://doaj.org/article/5a3c4fa046de42e2b39b7ea02305a170
رقم الأكسشن: edsdoj.5a3c4fa046de42e2b39b7ea02305a170
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:23130245
23130261
DOI:10.22363/2313-0245-2018-22-3-322-331