دورية أكاديمية
Nanopore-based Fourth-generation DNA Sequencing Technology
| العنوان: | Nanopore-based Fourth-generation DNA Sequencing Technology |
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| المؤلفون: | Yanxiao Feng, Yuechuan Zhang, Cuifeng Ying, Deqiang Wang, Chunlei Du |
| المصدر: | Genomics, Proteomics & Bioinformatics, Vol 13, Iss 1, Pp 4-16 (2015) |
| بيانات النشر: | Oxford University Press, 2015. |
| سنة النشر: | 2015 |
| المجموعة: | LCC:Biology (General) LCC:Computer applications to medicine. Medical informatics |
| مصطلحات موضوعية: | Nanopore, DNA sequencing, Single base, Single molecule, Biology (General), QH301-705.5, Computer applications to medicine. Medical informatics, R858-859.7 |
| الوصف: | Nanopore-based sequencers, as the fourth-generation DNA sequencing technology, have the potential to quickly and reliably sequence the entire human genome for less than $1000, and possibly for even less than $100. The single-molecule techniques used by this technology allow us to further study the interaction between DNA and protein, as well as between protein and protein. Nanopore analysis opens a new door to molecular biology investigation at the single-molecule scale. In this article, we have reviewed academic achievements in nanopore technology from the past as well as the latest advances, including both biological and solid-state nanopores, and discussed their recent and potential applications. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1672-0229 |
| Relation: | http://www.sciencedirect.com/science/article/pii/S1672022915000133; https://doaj.org/toc/1672-0229 |
| DOI: | 10.1016/j.gpb.2015.01.009 |
| URL الوصول: | https://doaj.org/article/5a91304a27934b378c99f345eb691594 |
| رقم الأكسشن: | edsdoj.5a91304a27934b378c99f345eb691594 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 16720229 |
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| DOI: | 10.1016/j.gpb.2015.01.009 |