Crosstalks between mTORC1 and mTORC2 variagate cytokine signaling to control NK maturation and effector function

التفاصيل البيبلوغرافية
العنوان:	Crosstalks between mTORC1 and mTORC2 variagate cytokine signaling to control NK maturation and effector function
المؤلفون:	Fangjie Wang, Meng Meng, Banghui Mo, Yao Yang, Yan Ji, Pei Huang, Wenjing Lai, Xiaodong Pan, Tingting You, Hongqin Luo, Xiao Guan, Yafei Deng, Shunzong Yuan, Jianhong Chu, Michael Namaka, Tiffany Hughes, Lilin Ye, Jianhua Yu, Xiaohui Li, Youcai Deng
المصدر:	Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
بيانات النشر:	Nature Portfolio, 2018.
سنة النشر:	2018
المجموعة:	LCC:Science
مصطلحات موضوعية:	Science
الوصف:	The metabolic regulator protein family, mTOR, regulate natural killer (NK) cell development and function, but the underlying mechanism is unclear. Here, the authors show that Raptor/mTORC1 and Rictor/mTORC2 form a feedback crosstalk network to variegate cytokine and cellular signaling and modulate NK maturation and effector functions.
نوع الوثيقة:	article
وصف الملف:	electronic resource
اللغة:	English
تدمد:	2041-1723
Relation:	https://doaj.org/toc/2041-1723
DOI:	10.1038/s41467-018-07277-9
URL الوصول:	https://doaj.org/article/aed5a9a2b75b4c99ac71c6c1c1c72f87
رقم الأكسشن:	edsdoj.5a9a2b75b4c99ac71c6c1c1c72f87
قاعدة البيانات:	Directory of Open Access Journals

الوصف
تدمد:	20411723
DOI:	10.1038/s41467-018-07277-9