دورية أكاديمية
Impact of lifestyle modification on glycemic control in patients with type 2 diabetes mellitus
| العنوان: | Impact of lifestyle modification on glycemic control in patients with type 2 diabetes mellitus |
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| المؤلفون: | Nandita B Sanghani, Deepak N Parchwani, Kamlesh M Palandurkar, Amit M Shah, Jatin V Dhanani |
| المصدر: | Indian Journal of Endocrinology and Metabolism, Vol 17, Iss 6, Pp 1030-1039 (2013) |
| بيانات النشر: | Wolters Kluwer Medknow Publications, 2013. |
| سنة النشر: | 2013 |
| المجموعة: | LCC:Diseases of the endocrine glands. Clinical endocrinology LCC:Diseases of the digestive system. Gastroenterology |
| مصطلحات موضوعية: | Hemoglobin A1c, physical activity, structured exercise, type 2 diabetes mellitus, Diseases of the endocrine glands. Clinical endocrinology, RC648-665, Diseases of the digestive system. Gastroenterology, RC799-869 |
| الوصف: | Background: Current treatment guidelines support the role of lifestyle modification, in terms of increasing the quantity and quality of physical activity to achieve target glycemia in patients with type 2 diabetes mellitus. Objective: To assess the effect of structured exercise training and unstructured physical activity interventions on glycemic control. Materials and Methods: This was a randomized six-month exercise intervention study conducted with previously inactive 279 patients of type 2 diabetes mellitus. Before randomization, all enrolled T2DM participants (n: 300; 30 to 60 year old, having diabetes for more than a year with HbA1c levels of 6.5% or higher) entered a one-month run-in phase to reduce dropout and maintain adherence. Results: A recommendation to increase physical activity was beneficial (0.14% HbA1c reduction; P = 0.12), but was not bringing significantly declines in HbA1c, whereas, structured exercise training is associated with a significant HbA1c decline of 0.59%. ( P = 0.030). In a subgroup analysis limited to participants with a baseline HbA1c value > 7%, both the unstructured (0. 48%; P = 0.04) and structured exercise training (0.77%; P < 0.01) groups experienced significant decline in HbA1c Vs the control, whereas among participants with baseline hemoglobin A1c values less than 7%, significant reduction occurred only in the structured exercise training group. Changes in blood pressure; total cholesterol, HDL-cholesterol (high-density lipoprotein), LDL-cholesterol (low-density lipoprotein) and the atherogenic index factors did not statistically significantly differ within (baseline to follow-up) and among groups. Conclusion: Supervised structured training was more efficacious than unstructured activity in achieving declines in HbA1c. Although both structured and unstructured training provide benefits, only the former was associated with significant reductions in HbA1c levels. Therefore, T2DM patients should be stimulated to participate in specifically designed exercise intervention programs. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2230-8210 2230-9500 |
| Relation: | http://www.ijem.in/article.asp?issn=2230-8210;year=2013;volume=17;issue=6;spage=1030;epage=1039;aulast=Sanghani; https://doaj.org/toc/2230-8210; https://doaj.org/toc/2230-9500 |
| DOI: | 10.4103/2230-8210.122618 |
| URL الوصول: | https://doaj.org/article/5aa36cd8fee741649a09a84df4ed1f20 |
| رقم الأكسشن: | edsdoj.5aa36cd8fee741649a09a84df4ed1f20 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 22308210 22309500 |
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| DOI: | 10.4103/2230-8210.122618 |