دورية أكاديمية
DNA methylation patterns in umbilical cord blood from infants of methadone maintained opioid dependent mothers
| العنوان: | DNA methylation patterns in umbilical cord blood from infants of methadone maintained opioid dependent mothers |
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| المؤلفون: | Oluwatobi Adegboyega, Suhita Gayen nee’ Betal, Pedro Urday, Rachel Huang, Katherine Bodycot, Huda B. Al-Kouatly, Kolawole Solarin, Joanna S. Y. Chan, Sankar Addya, Rupsa C. Boelig, Zubair H. Aghai |
| المصدر: | Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024) |
| بيانات النشر: | Nature Portfolio, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Medicine LCC:Science |
| مصطلحات موضوعية: | Medicine, Science |
| الوصف: | Abstract Methadone maintenance treatment for opioid dependent mothers is standard of care. Infants of methadone maintained opioid dependent (MMOD) mothers have better outcomes compared to infants of opioid dependent mothers without treatment. However, when compared to non-exposed infants, infants of MMOD mothers are associated with worse outcomes. We conducted a pilot study to examine genome wide differential DNA methylation using cord blood samples from sixteen term and near-term infants of MMOD and opioid naïve mothers, excluding Infants with chorioamnionitis. A total of 152 differentially methylated loci were identified at a difference > + 2, |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2045-2322 |
| Relation: | https://doaj.org/toc/2045-2322 |
| DOI: | 10.1038/s41598-024-66899-w |
| URL الوصول: | https://doaj.org/article/5bc756145518432c9f258c3cdf9038d5 |
| رقم الأكسشن: | edsdoj.5bc756145518432c9f258c3cdf9038d5 |
| قاعدة البيانات: | Directory of Open Access Journals |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 20452322 |
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| DOI: | 10.1038/s41598-024-66899-w |