دورية أكاديمية

Lead-Discovery of bis-Aromatic Alkynes: A Novel Class of Herbicides

التفاصيل البيبلوغرافية
العنوان: Lead-Discovery of bis-Aromatic Alkynes: A Novel Class of Herbicides
المؤلفون: Jutta Glock, Peter D. J. Grootenhuis, Steven Bondy, Daniel D. Comer, Soan Cheng, Arthur Steiger, Martin Zeller, Grit Laue, Adrian Friedmann, Olivier Jacob, Mafalda Nina, Hans-Jürg Widmer, Klaus Kreuz, Julie E. Penzotti, Hans Brunner, James Allen, Thierry Niderman, Hans Ulrich Haas, Renold Chollet, Martin Eberle, Peter Renold, William Lutz, Jürg Ehrler, Marian Valentini, Markus Walti, Evelyne Sieger, Thomas Vettiger, G. Wayne Craig
المصدر: CHIMIA, Vol 62, Iss 1-2 (2008)
بيانات النشر: Swiss Chemical Society, 2008.
سنة النشر: 2008
المجموعة: LCC:Chemistry
مصطلحات موضوعية: Agrochemicals, Alkyne template, Combinatorial chemistry, Discovery, Sonogashira coupling, Chemistry, QD1-999
الوصف: The search for new active molecules with novel modes of action and desirable physical properties is an ongoing endeavour. This publication describes the follow-up chemistry of a biological hit discovered in the screening system of Novartis Crop Protection, the legacy agrochemical parent of Syngenta Crop Protection. This chemistry was optimized through classical synthetic methods and automated parallel synthesis with coverage of important physical properties such as lipophilicity or Clog P and solubility. Preliminary biological activity from the greenhouse and field data with symptomology is presented.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: German
English
French
تدمد: 0009-4293
2673-2424
Relation: https://chimia.ch/chimia/article/view/4428; https://doaj.org/toc/0009-4293; https://doaj.org/toc/2673-2424
DOI: 10.2533/chimia.2008.23
URL الوصول: https://doaj.org/article/5c120d9f6ae7458abd6d1d641fce6442
رقم الأكسشن: edsdoj.5c120d9f6ae7458abd6d1d641fce6442
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:00094293
26732424
DOI:10.2533/chimia.2008.23