دورية أكاديمية
أعرض في EDS

Long-term Outcomes and Predictors of Chronic Thromboembolic Pulmonary Hypertension After Pulmonary Endarterectomy

التفاصيل البيبلوغرافية
العنوان: Long-term Outcomes and Predictors of Chronic Thromboembolic Pulmonary Hypertension After Pulmonary Endarterectomy
المؤلفون: Shuai Sun BS, Ji-Feng Li MD, PhD, Lin Liu MS, Ran Miao MD, PhD, Su-Qiao Yang MD, PhD, Tu-Guang Kuang MD, PhD, Juan-Ni Gong MD, PhD, Song Gu MD, PhD, Yan Liu MD, PhD, Yuan-Hua Yang MD, PhD
المصدر: Clinical and Applied Thrombosis/Hemostasis, Vol 28 (2022)
بيانات النشر: SAGE Publishing, 2022.
سنة النشر: 2022
المجموعة: LCC:Diseases of the circulatory (Cardiovascular) system
مصطلحات موضوعية: Diseases of the circulatory (Cardiovascular) system, RC666-701
الوصف: Background Pulmonary endarterectomy (PEA) is the preferred treatment for CTEPH patients which can significantly improve symptoms and pulmonary hemodynamics. Therefore, this retrospective study evaluated the long-term outcomes after pulmonary endarterectomy (PEA) and analyze the predictors of long-term outcomes for chronic thromboembolic pulmonary hypertension (CTEPH). Methods From 2002–2020, 76 CTEPH patients successfully discharged after PEA in Beijing Chaoyang Hospital were followed-up by scheduled clinical visits or telephone interviews. The follow-up time lasted for 18 years and median time was 7.29 years. Results The survival rate at 1,3,5,10,15 years postoperatively was 100.00%, 97.10%, 95.40%, 89.80% and 82.90%, respectively. Multivariate logistics regression analysis showed that postoperative mPAP (hazard ratio: 1.144; 95%confidence interval: 1.018–1.285; P = 0.023) was associated with a higher risk of late death, right atrium right and left diameters (hazard ratio: 1.113; 95%confidence interval, 1.006–1.231; P = 0.038) were associated with a higher risk of major adverse events. Conclusion Pulmonary endarterectomy is an effective way to treat CTEPH. Long-term outcome is excellent for patients who undergoing pulmonary endarterectomy who survived from peri-operation time. Postoperative mPAP is a significant prognostic factor for long-term death and right atrium right and left diameters is a significant prognostic factor for major adverse events. That shows patients with high postoperative mPAP and right atrium right and left diameter should be followed up closely.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1938-2723
10760296
29538521
Relation: https://doaj.org/toc/1938-2723
DOI: 10.1177/10760296221140882
URL الوصول: https://doaj.org/article/5c29538521c24ec6b48a2254f3e27cda
رقم الأكسشن: edsdoj.5c29538521c24ec6b48a2254f3e27cda
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:19382723
10760296
29538521
DOI:10.1177/10760296221140882