دورية أكاديمية
Long-term Outcomes and Predictors of Chronic Thromboembolic Pulmonary Hypertension After Pulmonary Endarterectomy
العنوان: | Long-term Outcomes and Predictors of Chronic Thromboembolic Pulmonary Hypertension After Pulmonary Endarterectomy |
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المؤلفون: | Shuai Sun BS, Ji-Feng Li MD, PhD, Lin Liu MS, Ran Miao MD, PhD, Su-Qiao Yang MD, PhD, Tu-Guang Kuang MD, PhD, Juan-Ni Gong MD, PhD, Song Gu MD, PhD, Yan Liu MD, PhD, Yuan-Hua Yang MD, PhD |
المصدر: | Clinical and Applied Thrombosis/Hemostasis, Vol 28 (2022) |
بيانات النشر: | SAGE Publishing, 2022. |
سنة النشر: | 2022 |
المجموعة: | LCC:Diseases of the circulatory (Cardiovascular) system |
مصطلحات موضوعية: | Diseases of the circulatory (Cardiovascular) system, RC666-701 |
الوصف: | Background Pulmonary endarterectomy (PEA) is the preferred treatment for CTEPH patients which can significantly improve symptoms and pulmonary hemodynamics. Therefore, this retrospective study evaluated the long-term outcomes after pulmonary endarterectomy (PEA) and analyze the predictors of long-term outcomes for chronic thromboembolic pulmonary hypertension (CTEPH). Methods From 2002–2020, 76 CTEPH patients successfully discharged after PEA in Beijing Chaoyang Hospital were followed-up by scheduled clinical visits or telephone interviews. The follow-up time lasted for 18 years and median time was 7.29 years. Results The survival rate at 1,3,5,10,15 years postoperatively was 100.00%, 97.10%, 95.40%, 89.80% and 82.90%, respectively. Multivariate logistics regression analysis showed that postoperative mPAP (hazard ratio: 1.144; 95%confidence interval: 1.018–1.285; P = 0.023) was associated with a higher risk of late death, right atrium right and left diameters (hazard ratio: 1.113; 95%confidence interval, 1.006–1.231; P = 0.038) were associated with a higher risk of major adverse events. Conclusion Pulmonary endarterectomy is an effective way to treat CTEPH. Long-term outcome is excellent for patients who undergoing pulmonary endarterectomy who survived from peri-operation time. Postoperative mPAP is a significant prognostic factor for long-term death and right atrium right and left diameters is a significant prognostic factor for major adverse events. That shows patients with high postoperative mPAP and right atrium right and left diameter should be followed up closely. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 1938-2723 10760296 29538521 |
Relation: | https://doaj.org/toc/1938-2723 |
DOI: | 10.1177/10760296221140882 |
URL الوصول: | https://doaj.org/article/5c29538521c24ec6b48a2254f3e27cda |
رقم الأكسشن: | edsdoj.5c29538521c24ec6b48a2254f3e27cda |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 19382723 10760296 29538521 |
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DOI: | 10.1177/10760296221140882 |