دورية أكاديمية

Diagnosis and Management of Dysgerminomas with a Brief Summary of Primitive Germ Cell Tumors

التفاصيل البيبلوغرافية
العنوان: Diagnosis and Management of Dysgerminomas with a Brief Summary of Primitive Germ Cell Tumors
المؤلفون: Melinda-Ildiko Mitranovici, Diana Maria Chiorean, Maria Cezara Mureșan, Corneliu-Florin Buicu, Raluca Moraru, Liviu Moraru, Titiana Cornelia Cotoi, Ovidiu Simion Cotoi, Havva Serap Toru, Adrian Apostol, Sabin Gligore Turdean, Claudiu Mărginean, Ion Petre, Ioan Emilian Oală, Zsuzsanna Simon-Szabo, Viviana Ivan, Lucian Pușcașiu
المصدر: Diagnostics, Vol 12, Iss 12, p 3105 (2022)
بيانات النشر: MDPI AG, 2022.
سنة النشر: 2022
المجموعة: LCC:Medicine (General)
مصطلحات موضوعية: dysgerminoma, OMGCTs, platinum-based therapy, heterogenous tumors, epigenetics, primitive germ cell tumors, Medicine (General), R5-920
الوصف: Dysgerminoma represents a rare malignant tumor composed of germ cells, originally from the embryonic gonads. Regarding its incidence, we do not have precise data due to its rarity. Dysgerminoma occurs at a fertile age. The preferred treatment is the surgical removal of the tumor succeeded by the preservation of fertility. Even if a multidisciplinary team, founded in 2009 by a gynecologist, an oncologist, a pediatric oncologist and a pediatric surgeon, under the guidance of the Malignant Germ Cell International Consortium (MaGIC), studies this type of tumor, issues still remain related to the lack of a randomized study and to both the management and understanding of the concept of OMGCTs (ovarian malignant germ cell tumors). The aim of this review is to present from the literature the various approaches for this type of tumor, and, regarding innovative therapies or possible prevention, which can be applied in clinical practice. Multidisciplinarity and treatment in reference centers have proven their usefulness as well.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2075-4418
Relation: https://www.mdpi.com/2075-4418/12/12/3105; https://doaj.org/toc/2075-4418
DOI: 10.3390/diagnostics12123105
URL الوصول: https://doaj.org/article/5c5945db46c64b7ba83ad33674796039
رقم الأكسشن: edsdoj.5c5945db46c64b7ba83ad33674796039
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:20754418
DOI:10.3390/diagnostics12123105