دورية أكاديمية

Prevalence and Trends of Staphylococcus aureus Bacteraemia in Hospitalized Patients in South Africa, 2010 to 2012: Laboratory-Based Surveillance Mapping of Antimicrobial Resistance and Molecular Epidemiology.

التفاصيل البيبلوغرافية
العنوان: Prevalence and Trends of Staphylococcus aureus Bacteraemia in Hospitalized Patients in South Africa, 2010 to 2012: Laboratory-Based Surveillance Mapping of Antimicrobial Resistance and Molecular Epidemiology.
المؤلفون: Olga Perovic, Samantha Iyaloo, Ranmini Kularatne, Warren Lowman, Noma Bosman, Jeannette Wadula, Sharona Seetharam, Adriano Duse, Nontombi Mbelle, Colleen Bamford, Halima Dawood, Yesholata Mahabeer, Prathna Bhola, Shareef Abrahams, Ashika Singh-Moodley
المصدر: PLoS ONE, Vol 10, Iss 12, p e0145429 (2015)
بيانات النشر: Public Library of Science (PLoS), 2015.
سنة النشر: 2015
المجموعة: LCC:Medicine
LCC:Science
مصطلحات موضوعية: Medicine, Science
الوصف: INTRODUCTION:We aimed to obtain an in-depth understanding on recent antimicrobial resistance trends and molecular epidemiology trends of S. aureus bacteraemia (SAB). METHODS:Thirteen academic centres in South Africa were included from June 2010 until July 2012. S. aureus susceptibility testing was performed on the MicroScan Walkaway. Real-time PCR using the LightCycler 480 II was done for mecA and nuc. SCCmec and spa-typing were finalized with conventional PCR. We selected one isolate per common spa type per province for multilocus sequence typing (MLST). RESULTS:S. aureus from 2709 patients were included, and 1231 (46%) were resistant to methicillin, with a significant decline over the three-year period (p-value = 0.003). Geographical distribution of MRSA was significantly higher in Gauteng compared to the other provinces (P
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1932-6203
Relation: http://europepmc.org/articles/PMC4697812?pdf=render; https://doaj.org/toc/1932-6203
DOI: 10.1371/journal.pone.0145429
URL الوصول: https://doaj.org/article/5c5a3b397a3b4909804292c90e329f6c
رقم الأكسشن: edsdoj.5c5a3b397a3b4909804292c90e329f6c
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:19326203
DOI:10.1371/journal.pone.0145429