دورية أكاديمية
Prevalence and Trends of Staphylococcus aureus Bacteraemia in Hospitalized Patients in South Africa, 2010 to 2012: Laboratory-Based Surveillance Mapping of Antimicrobial Resistance and Molecular Epidemiology.
العنوان: | Prevalence and Trends of Staphylococcus aureus Bacteraemia in Hospitalized Patients in South Africa, 2010 to 2012: Laboratory-Based Surveillance Mapping of Antimicrobial Resistance and Molecular Epidemiology. |
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المؤلفون: | Olga Perovic, Samantha Iyaloo, Ranmini Kularatne, Warren Lowman, Noma Bosman, Jeannette Wadula, Sharona Seetharam, Adriano Duse, Nontombi Mbelle, Colleen Bamford, Halima Dawood, Yesholata Mahabeer, Prathna Bhola, Shareef Abrahams, Ashika Singh-Moodley |
المصدر: | PLoS ONE, Vol 10, Iss 12, p e0145429 (2015) |
بيانات النشر: | Public Library of Science (PLoS), 2015. |
سنة النشر: | 2015 |
المجموعة: | LCC:Medicine LCC:Science |
مصطلحات موضوعية: | Medicine, Science |
الوصف: | INTRODUCTION:We aimed to obtain an in-depth understanding on recent antimicrobial resistance trends and molecular epidemiology trends of S. aureus bacteraemia (SAB). METHODS:Thirteen academic centres in South Africa were included from June 2010 until July 2012. S. aureus susceptibility testing was performed on the MicroScan Walkaway. Real-time PCR using the LightCycler 480 II was done for mecA and nuc. SCCmec and spa-typing were finalized with conventional PCR. We selected one isolate per common spa type per province for multilocus sequence typing (MLST). RESULTS:S. aureus from 2709 patients were included, and 1231 (46%) were resistant to methicillin, with a significant decline over the three-year period (p-value = 0.003). Geographical distribution of MRSA was significantly higher in Gauteng compared to the other provinces (P |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 1932-6203 |
Relation: | http://europepmc.org/articles/PMC4697812?pdf=render; https://doaj.org/toc/1932-6203 |
DOI: | 10.1371/journal.pone.0145429 |
URL الوصول: | https://doaj.org/article/5c5a3b397a3b4909804292c90e329f6c |
رقم الأكسشن: | edsdoj.5c5a3b397a3b4909804292c90e329f6c |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 19326203 |
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DOI: | 10.1371/journal.pone.0145429 |