دورية أكاديمية
Renal failure and pleural effusion; a diagnostic challenge
| العنوان: | Renal failure and pleural effusion; a diagnostic challenge |
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| المؤلفون: | Sara Cardoso Fernandes, Joana Marques, Mário Pinto, Mário Góis, Helena Sousa, Fernando Nolasco |
| المصدر: | Journal of Nephropathology, Vol 12, Iss 3, Pp e17309-e17309 (2023) |
| بيانات النشر: | Society of Diabetic Nephropathy Prevention, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Pathology LCC:Internal medicine LCC:Other systems of medicine |
| مصطلحات موضوعية: | sjögren’s syndrome, aa amyloidosis, renal amyloidosis, pleural amyloidosis, Pathology, RB1-214, Internal medicine, RC31-1245, Other systems of medicine, RZ201-999 |
| الوصف: | Sjögren’s syndrome is a chronic inflammatory disorder mostly involving the exocrine glands. Extraglandular disease may occur in up to one quarter of patients. Kidney involvement is rare, more often manifested by tubular dysfunction secondary to tubulointerstitial nephritis. Primary glomerular disease is uncommon. The authors present the case of a 73-year-old woman with xerostomia and positivity for anti-Ro and anti-La antibodies admitted for acute kidney injury and exudative pleural effusion. Biopsy of salivary glands was compatible with Sjögren’s syndrome. Extraglandular involvement was also confirmed by renal and pleural deposition of AA-amyloid. The patient was started on prednisolone followed by azathioprine with rapid improvement of lung disease. However, due to progressing renal disease and clinical deterioration, prognosis was guarded and the patient died. We describe a case of secondary amyloidosis with systemic involvement and infrequent clinical manifestations, briefly reviewing the key aspects of Sjögren’s syndrome and AA-amyloidosis. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2251-8363 2251-8819 |
| Relation: | https://nephropathol.com/PDF/jnp-12-e17309.pdf; https://doaj.org/toc/2251-8363; https://doaj.org/toc/2251-8819 |
| DOI: | 10.34172/jnp.2023.17309 |
| URL الوصول: | https://doaj.org/article/5cae0f01125b4f1489b181519a223eab |
| رقم الأكسشن: | edsdoj.5cae0f01125b4f1489b181519a223eab |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 22518363 22518819 |
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| DOI: | 10.34172/jnp.2023.17309 |