Enzymology of Ca2+-Mobilizing Second Messengers Derived from NAD: From NAD Glycohydrolases to (Dual) NADPH Oxidases

التفاصيل البيبلوغرافية
العنوان:	Enzymology of Ca2+-Mobilizing Second Messengers Derived from NAD: From NAD Glycohydrolases to (Dual) NADPH Oxidases
المؤلفون:	Andreas H. Guse
المصدر:	Cells, Vol 12, Iss 4, p 675 (2023)
بيانات النشر:	MDPI AG, 2023.
سنة النشر:	2023
المجموعة:	LCC:Cytology
مصطلحات موضوعية:	Ca2+ signaling, NAD(P), ADPR, cADPR, NAADP, NAD glycohydrolase, Cytology, QH573-671
الوصف:	Nicotinamide adenine dinucleotide (NAD) and its 2′-phosphorylated cousin NADP are precursors for the enzymatic formation of the Ca2+-mobilizing second messengers adenosine diphosphoribose (ADPR), 2′-deoxy-ADPR, cyclic ADPR, and nicotinic acid adenine dinucleotide phosphate (NAADP). The enzymes involved are either NAD glycohydrolases CD38 or sterile alpha toll/interleukin receptor motif containing-1 (SARM1), or (dual) NADPH oxidases (NOX/DUOX). Enzymatic function(s) are reviewed and physiological role(s) in selected cell systems are discussed.
نوع الوثيقة:	article
وصف الملف:	electronic resource
اللغة:	English
تدمد:	2073-4409
Relation:	https://www.mdpi.com/2073-4409/12/4/675; https://doaj.org/toc/2073-4409
DOI:	10.3390/cells12040675
URL الوصول:	https://doaj.org/article/5d1fa3c7375a4c1c849a8db446e59961
رقم الأكسشن:	edsdoj.5d1fa3c7375a4c1c849a8db446e59961
قاعدة البيانات:	Directory of Open Access Journals

الوصف
تدمد:	20734409
DOI:	10.3390/cells12040675