دورية أكاديمية

Automatic treatment planning improves the clinical quality of head and neck cancer treatment plans

التفاصيل البيبلوغرافية
العنوان: Automatic treatment planning improves the clinical quality of head and neck cancer treatment plans
المؤلفون: Christian Rønn Hansen, Anders Bertelsen, Irene Hazell, Ruta Zukauskaite, Niels Gyldenkerne, Jørgen Johansen, Jesper G. Eriksen, Carsten Brink
المصدر: Clinical and Translational Radiation Oncology, Vol 1, Iss C, Pp 2-8 (2016)
بيانات النشر: Elsevier, 2016.
سنة النشر: 2016
المجموعة: LCC:Medical physics. Medical radiology. Nuclear medicine
LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens
مصطلحات موضوعية: Automatic, Treatment planning, Head and neck, VMAT, Pinnacle, Medical physics. Medical radiology. Nuclear medicine, R895-920, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
الوصف: Background: Treatment plans for head and neck (H&N) cancer are highly complex due to multiple dose prescription levels and numerous organs at risk (OARs) close to the target. The plan quality is inter-planner dependent since it is dependent on the skills and experience of the dosimetrist. This study presents a blinded prospective clinical comparison of automatic (AU) and manually (MA) generated H&N VMAT plans made for clinical use. Methods: MA and AU plans were generated for 30 consecutive patients in Pinnacle3 using the IMRT optimisation module and the new Autoplan module, respectively. The plan quality was blindedly compared by three senior oncologists and the best plan was selected for treatment of the patient. Planning time was measured as the active operator time used. The plan quality was analysed with DVH metrics and the dose delivery accuracy validated on the ArcCheck phantom. Results: For twenty-nine out of the thirty patients the AU plan was chosen for treatment. Target doses were more homogenous with the AU plans and the OAR doses were significantly reduced, between 0.5 and 6.5 Gy. The average operator time spent on creating a manual plan was 64 min which was halved by Autoplan. The AU plans were more modulated as illustrated by an increase in MUs, which might cause the slightly lower pass rate of 97.7% in the ArcCheck measurements. Conclusions: Target doses were similar between MA and AU plan, while AU plans spared all OAR considerably better than the MA plans.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2405-6308
Relation: http://www.sciencedirect.com/science/article/pii/S2405630816300040; https://doaj.org/toc/2405-6308
DOI: 10.1016/j.ctro.2016.08.001
URL الوصول: https://doaj.org/article/5d86df2a87d444b1aed00ceee694a2a8
رقم الأكسشن: edsdoj.5d86df2a87d444b1aed00ceee694a2a8
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:24056308
DOI:10.1016/j.ctro.2016.08.001