دورية أكاديمية
Five-Year Antimicrobial Resistance Patterns of Urinary Escherichia coli at an Australian Tertiary Hospital: Time Series Analyses of Prevalence Data.
العنوان: | Five-Year Antimicrobial Resistance Patterns of Urinary Escherichia coli at an Australian Tertiary Hospital: Time Series Analyses of Prevalence Data. |
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المؤلفون: | Oyebola Fasugba, Brett G Mitchell, George Mnatzaganian, Anindita Das, Peter Collignon, Anne Gardner |
المصدر: | PLoS ONE, Vol 11, Iss 10, p e0164306 (2016) |
بيانات النشر: | Public Library of Science (PLoS), 2016. |
سنة النشر: | 2016 |
المجموعة: | LCC:Medicine LCC:Science |
مصطلحات موضوعية: | Medicine, Science |
الوصف: | This study describes the antimicrobial resistance temporal trends and seasonal variation of Escherichia coli (E. coli) urinary tract infections (UTIs) over five years, from 2009 to 2013, and compares prevalence of resistance in hospital- and community-acquired E. coli UTI. A cross sectional study of E. coli UTIs from patients attending a tertiary referral hospital in Canberra, Australia was undertaken. Time series analysis was performed to illustrate resistance trends. Only the first positive E. coli UTI per patient per year was included in the analysis. A total of 15,022 positive cultures from 8724 patients were identified. Results are based on 5333 first E. coli UTIs, from 4732 patients, of which 84.2% were community-acquired. Five-year hospital and community resistance rates were highest for ampicillin (41.9%) and trimethoprim (20.7%). Resistance was lowest for meropenem (0.0%), nitrofurantoin (2.7%), piperacillin-tazobactam (2.9%) and ciprofloxacin (6.5%). Resistance to amoxycillin-clavulanate, cefazolin, gentamicin and piperacillin-tazobactam were significantly higher in hospital- compared to community-acquired UTIs (9.3% versus 6.2%; 15.4% versus 9.7%; 5.2% versus 3.7% and 5.2% versus 2.5%, respectively). Trend analysis showed significant increases in resistance over five years for amoxycillin-clavulanate, trimethoprim, ciprofloxacin, nitrofurantoin, trimethoprim-sulphamethoxazole, cefazolin, ceftriaxone and gentamicin (P |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 1932-6203 74714805 |
Relation: | http://europepmc.org/articles/PMC5053592?pdf=render; https://doaj.org/toc/1932-6203 |
DOI: | 10.1371/journal.pone.0164306 |
URL الوصول: | https://doaj.org/article/5dba0b2c5ec74714805919f7ea28a9fa |
رقم الأكسشن: | edsdoj.5dba0b2c5ec74714805919f7ea28a9fa |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 19326203 74714805 |
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DOI: | 10.1371/journal.pone.0164306 |