دورية أكاديمية
The epigenetic regulator LSH maintains fork protection and genomic stability via MacroH2A deposition and RAD51 filament formation
| العنوان: | The epigenetic regulator LSH maintains fork protection and genomic stability via MacroH2A deposition and RAD51 filament formation |
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| المؤلفون: | Xiaoping Xu, Kai Ni, Yafeng He, Jianke Ren, Chongkui Sun, Yie Liu, Mirit I. Aladjem, Sandra Burkett, Richard Finney, Xia Ding, Shyam K. Sharan, Kathrin Muegge |
| المصدر: | Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021) |
| بيانات النشر: | Nature Portfolio, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Science |
| مصطلحات موضوعية: | Science |
| الوصف: | LSH/HELLS is a chromatin remodeler promoting incorporation of histone variant macroH2A. Here the authors reveal a role for LSH in genome stability, in protecting nascent DNA at stalled forks mediated by macroH2A deposition and RAD51 filament formation. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2041-1723 17259487 |
| Relation: | https://doaj.org/toc/2041-1723 |
| DOI: | 10.1038/s41467-021-23809-2 |
| URL الوصول: | https://doaj.org/article/5dd84ce1725948758084a5a36813c4ed |
| رقم الأكسشن: | edsdoj.5dd84ce1725948758084a5a36813c4ed |
| قاعدة البيانات: | Directory of Open Access Journals |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 20411723 17259487 |
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| DOI: | 10.1038/s41467-021-23809-2 |