التفاصيل البيبلوغرافية
العنوان:
Development of an oral once-weekly drug delivery system for HIV antiretroviral therapy
المؤلفون:
Ameya R. Kirtane , Omar Abouzid , Daniel Minahan , Taylor Bensel , Alison L. Hill , Christian Selinger , Anna Bershteyn , Morgan Craig , Shirley S. Mo , Hormoz Mazdiyasni , Cody Cleveland , Jaimie Rogner , Young-Ah Lucy Lee , Lucas Booth , Farhad Javid , Sarah J. Wu , Tyler Grant , Andrew M. Bellinger , Boris Nikolic , Alison Hayward , Lowell Wood , Philip A. Eckhoff , Martin A. Nowak , Robert Langer , Giovanni Traverso
المصدر:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
بيانات النشر:
Nature Portfolio, 2018.
سنة النشر:
2018
المجموعة:
LCC:Science
مصطلحات موضوعية:
Science
الوصف:
Poor adherence to daily antiretrovirals can significantly affect treatment efficacy, but oral long-acting antiretrovirals are currently lacking. Here, the authors develop a once-weekly oral dosage form for anti-HIV drugs, assess its pharmacokinetics in pigs, and model its impact on viral resistance and disease epidemics.
نوع الوثيقة:
article
وصف الملف:
electronic resource
اللغة:
English
تدمد:
2041-1723
Relation:
https://doaj.org/toc/2041-1723
DOI:
10.1038/s41467-017-02294-6
URL الوصول:
https://doaj.org/article/5de2bff495f541e8ae208242e10f066e
رقم الأكسشن:
edsdoj.5de2bff495f541e8ae208242e10f066e
قاعدة البيانات:
Directory of Open Access Journals
Full Text Finder