دورية أكاديمية
أعرض في EDS

Prognostic impact of lymphovascular and perineural invasion in squamous cell carcinoma of the tongue

التفاصيل البيبلوغرافية
العنوان: Prognostic impact of lymphovascular and perineural invasion in squamous cell carcinoma of the tongue
المؤلفون: Qiongling Huang, Yanjun Huang, Chunhui Chen, Yizheng Zhang, Jiao Zhou, Chengke Xie, Ming Lu, Yu Xiong, Dage Fang, Yubin Yang, Weipeng Hu, Feng Zheng, Chaohui Zheng
المصدر: Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
بيانات النشر: Nature Portfolio, 2023.
سنة النشر: 2023
المجموعة: LCC:Medicine
LCC:Science
مصطلحات موضوعية: Medicine, Science
الوصف: Abstract This study aimed to investigate the prognostic impact of lymphovascular and perineural invasions in patients with squamous cell carcinoma of the tongue who received surgery-based treatment at our institution between January 2013 and December 2020. Patients were divided into four groups based on the presence of perineural (P−/P +) and lymphovascular invasions (V−/V +): P–V−, P–V + , P + V−, and P + V + . Log-rank and Cox proportional hazard models were used to evaluate the association between perineural /lymphovascular invasion and overall survival (OS). Altogether, 127 patients were included, and 95 (74.8%), 8 (6.3%), 18 (14.2%), and 6 (4.7%) cases were classified as P–V−, P–V + , P + V−, and P + V + , respectively. Pathologic N stage (pN stage), tumor stage, histological grade, lymphovascular invasion, perineural invasion, and postoperative radiotherapy were significantly associated with OS (p
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2045-2322
Relation: https://doaj.org/toc/2045-2322
DOI: 10.1038/s41598-023-30939-8
URL الوصول: https://doaj.org/article/5e044becaaab489e9927304969c3893c
رقم الأكسشن: edsdoj.5e044becaaab489e9927304969c3893c
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:20452322
DOI:10.1038/s41598-023-30939-8