دورية أكاديمية
Maternal serum autotaxin levels in early- and late-onset preeclampsia
| العنوان: | Maternal serum autotaxin levels in early- and late-onset preeclampsia |
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| المؤلفون: | Hakan Erenel, Nevin Yilmaz, Tayfur Cift, Berk Bulut, Isik Sozen, Berna Aslan Cetin, Altay Gezer, Hakan Ekmekci, Baris Kaya, Abdullah Tuten |
| المصدر: | Hypertension in Pregnancy, Vol 36, Iss 4, Pp 310-314 (2017) |
| بيانات النشر: | Taylor & Francis Group, 2017. |
| سنة النشر: | 2017 |
| المجموعة: | LCC:Gynecology and obstetrics |
| مصطلحات موضوعية: | preeclampsia, autotaxin, pregnancy, early-onset preeclampsia, late-onset preeclampsia, Gynecology and obstetrics, RG1-991 |
| الوصف: | Purpose: We aimed to compare the serum autotaxin levels in early- and late- preeclamptic and healthy pregnant patients at a university hospital. Methods: A total of 55 singleton preeclamptic women who delivered at Cerrahpasa Medical Faculty were included in the study. The patients were subdivided into two groups: early-onset preeclampsia (n = 31) and late-onset preeclampsia (n = 24). Demographic and clinical data were compared between early-onset and late-onset preeclamptic patients. The control group was composed of 32 healthy pregnant patients. Results: The mean autotaxin levels were 1.16 ± 0.97 and 0.7 ± 0.35 ng/ml in the early- and late-onset preeclampsia groups, respectively. Autotaxin levels were significantly higher in early-onset preeclampsia group compared with late-onset preeclampsia group. Autotaxin levels were found to be significantly higher in preeclamptic patients compared with control group. Serum autotaxin levels showed a significant positive correlation with maternal systolic, diastolic blood pressures and uric acid levels. Conclusion: Autotaxin might be a promising marker for detecting early-onset preeclampsia. However, further studies are necessary to confirm this hypothesis. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1064-1955 1525-6065 10641955 |
| Relation: | https://doaj.org/toc/1064-1955; https://doaj.org/toc/1525-6065 |
| DOI: | 10.1080/10641955.2017.1388389 |
| URL الوصول: | https://doaj.org/article/a5e31834d397423ab1a1134daaf5e277 |
| رقم الأكسشن: | edsdoj.5e31834d397423ab1a1134daaf5e277 |
| قاعدة البيانات: | Directory of Open Access Journals |
PDF full text from Publisher | تدمد: | 10641955 15256065 |
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| DOI: | 10.1080/10641955.2017.1388389 |