دورية أكاديمية
The spatial distribution of interleukin-4 (IL-4) reference values in China based on a back propagation (BP) neural network
العنوان: | The spatial distribution of interleukin-4 (IL-4) reference values in China based on a back propagation (BP) neural network |
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المؤلفون: | Zhao Rong Huang, Miao Ge, Xin Rui Pang, Pu Song, Congxia Wang |
المصدر: | Geospatial Health, Vol 18, Iss 2 (2023) |
بيانات النشر: | PAGEPress Publications, 2023. |
سنة النشر: | 2023 |
المجموعة: | LCC:Geography (General) |
مصطلحات موضوعية: | IL-4, geographical factors, correlation analysis, BP neural network, Kriging interpolation, China, Geography (General), G1-922 |
الوصف: | This study aimed to investigate the geospatial distribution of normal reference values of Interleukin 4 (IL-4) in healthy Chinese adults and to provide a basis for the development of standard references. IL-4 values of 5,221 healthy adults from 64 cities in China were collected and analyzed for a potential correlation with 24 topographical, climatic and soil factors. Seven of these factors were extracted and used to build a back propagation (BP) neural network model that was used to predict IL-4 reference values in healthy individuals from 2,317 observation sites nationwide. The predicted values were tested for normality and geographic distribution by analytic Kriging interpolation to map the geographic distribution of IL-4 reference values in healthy Chinese subjects. The results showed that IL-4 values generally decreased and then increased from the South to the North. We concluded that the BP neural network model applies to this approach, where certain geographical factors determine levels of various biochemical and immunological standards in healthy adults in regions with different topography, climate and soil indices. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 1827-1987 1970-7096 |
Relation: | https://geospatialhealth.net/index.php/gh/article/view/1197; https://doaj.org/toc/1827-1987; https://doaj.org/toc/1970-7096 |
DOI: | 10.4081/gh.2023.1197 |
URL الوصول: | https://doaj.org/article/5e4a09ec7c8c4eebbea6ab28b6319cf0 |
رقم الأكسشن: | edsdoj.5e4a09ec7c8c4eebbea6ab28b6319cf0 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 18271987 19707096 |
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DOI: | 10.4081/gh.2023.1197 |