دورية أكاديمية
أعرض في EDS

A comparison of two types of contrast media used in endoscopic retrograde cholangiopancreatography: A retrospective study.

التفاصيل البيبلوغرافية
العنوان: A comparison of two types of contrast media used in endoscopic retrograde cholangiopancreatography: A retrospective study.
المؤلفون: Tomoharu Matsuura, Yasushi Hamaya, Shunya Onoue, Satoshi Tamura, Natsuki Ishida, Mihoko Yamade, Shinya Tani, Moriya Iwaizumi, Satoshi Osawa, Takahisa Furuta, Ken Sugimoto
المصدر: PLoS ONE, Vol 18, Iss 1, p e0280279 (2023)
بيانات النشر: Public Library of Science (PLoS), 2023.
سنة النشر: 2023
المجموعة: LCC:Medicine
LCC:Science
مصطلحات موضوعية: Medicine, Science
الوصف: BackgroundPost-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) is one of the most serious complications of ERCP. Various procedures can reduce the incidence of PEP, such as wire-guided cannulation, prophylactic pancreatic stent placement, and pretreatment anal insertion of NSAIDs. Recently, iso-osmolar contrast media (IOCM) have been used for ERCP in several hospitals to reduce the risk of PEP in Japan. However, the effect of IOCM is uncertain because few reports have examined IOCM in relation to PEP.AimThis study aimed to investigate the relationship between contrast media used and the incidence of PEP.MethodsThis retrospective study included all qualifying patients who had undergone ERCP at Hamamatsu University Hospital between January 2012 and January 2020. This study examined whether there was a difference in the onset of PEP between patients administered IOCM and high osmolar contrast medium (HOCM). Propensity score matching was used to analyze patient characteristics and ERCP procedures. Amidotrizoic acid was used as HOCM and iodixanol as IOCM.ResultsERCP was performed on 458 patients, and 830 procedures were conducted. After propensity score matching, 162 patients from the amidotrizoic acid group and 162 patients from the iodixanol group were selected. The incidence of PEP was 10.5% (17) in the amidotrizoic acid group and 9.3% (15) in the iodixanol group (P = 0.71). Changes in serum amylase levels post- and pre-ERCP were 240.6 ± 573.8 U/L and 142.7 ± 382.1 U/L in the amidotrizoic acid and iodixanol groups, respectively (P = 0.072).ConclusionIodixanol had no prophylactic effect on PEP and clinical outcomes.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1932-6203
Relation: https://doaj.org/toc/1932-6203
DOI: 10.1371/journal.pone.0280279
URL الوصول: https://doaj.org/article/5ee4dae1c4ae469ca793541e2ac9c1e3
رقم الأكسشن: edsdoj.5ee4dae1c4ae469ca793541e2ac9c1e3
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:19326203
DOI:10.1371/journal.pone.0280279