With the rapid development of information technology and social media platforms, digitization has not only given rise to new types of urban vitality spaces but also profoundly changed traditional spatial forms and constructions through online and offline interactions. This study aims to analyze the characteristics and impacts of the changing virtual and physical vitality space forms in Guangzhou and adduce theoretical references and practical insights for urban development and vitality enhancement. Using POI data and TikTok check-in data, this study conducts a spatial analysis of the spatial characteristics and changes of virtual and physical vitality in Guangzhou. The results show that: (1) The spatial patterns of urban virtual and physical vitality generally show a cyclic structure of decreasing vitality from the central urban area to the peripheral areas, indicating that physical space is the basis for the operation of virtual space. (2) Online and offline digital interactions form three types of vitality spaces: a traditional vitality-enhancing space, traditional vitality-declining space, and new Internet celebrity space, whose spatial distribution characteristics differ, with the new Internet celebrity space showing a scattered and discrete distribution. (3) The impact of mobile short video digital platform on the vitality of different types of spaces is heterogeneous, with a boosting effect for scenic spots, leisure and entertainment spots, and sports and fitness spaces, while the impact on food and beverage spaces is smaller. Scenic spots, leisure and recreation spots, and sports and fitness spaces have less impact on spatial vitality, while commercial shopping has a significant heterogeneous impact on spatial vitality. This study seeks to demonstrate the validity of combining POI data and TikTok check-in data to explore the relationship between digitalization and urban vitality space along the digital and social media dimensions and to enrich the research method of urban vitality space. In addition, this study shows that: First, the impact of digitalization on urban spatial form should be emphasized and the role of digitalization in shaping urban vitality space should be fully recognized. Second, urban planning and construction should focus on the development trend of online and offline interaction and promote the integration and complementation of physical and virtual spaces by introducing digital technologies and means. In addition, different types of vitality spaces afford different development opportunities and challenges in the digital context, so corresponding development strategies should be formulated according to local conditions. Finally, exploring the relationship between digitalization and urban vitality spaces can help to clarify the new urban logic and further enhance urban vitality.
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