دورية أكاديمية
أعرض في EDS

CD8‐positive peripheral T cell lymphoma in a patient following long‐term nivolumab for advanced lung adenocarcinoma: A case report

التفاصيل البيبلوغرافية
العنوان: CD8‐positive peripheral T cell lymphoma in a patient following long‐term nivolumab for advanced lung adenocarcinoma: A case report
المؤلفون: Keigo Koda, Mikio Toyoshima, Shusuke Yazawa, Atsuki Fukada, Haruhiko Sugimura, Takafumi Suda
المصدر: Thoracic Cancer, Vol 12, Iss 11, Pp 1765-1769 (2021)
بيانات النشر: Wiley, 2021.
سنة النشر: 2021
المجموعة: LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens
مصطلحات موضوعية: immune checkpoint inhibitor, nivolumab, lung cancer, T cell lymphoma, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
الوصف: Abstract A 54‐year‐old male smoker presented with hemoptysis. Advanced lung adenocarcinoma, cT1cN3M1b, stage IVB, was diagnosed. Enlargement of multiple intraperitoneal and inguinal lymph nodes and peripheral atypical lymphocytosis appeared after 33 cycles of second‐line treatment with nivolumab, and a specimen obtained by left inguinal lymph node biopsy showed peripheral T cell lymphoma (PTCL), not otherwise specified. Lymphoma cells expressed CD3+, CD8+, and CD56+, but not CD4+ or PD‐1. Despite systemic chemotherapy with cyclophosphamide, hydroxydaunorubicin, oncovin, and prednisolone, the patient died of PTCL 864 days after the initial visit. The possible relationship between treatment with immune checkpoint inhibitors (ICIs) and PTCL development is discussed here.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1759-7714
1759-7706
Relation: https://doaj.org/toc/1759-7706; https://doaj.org/toc/1759-7714
DOI: 10.1111/1759-7714.13966
URL الوصول: https://doaj.org/article/606fc10c954446a4bc8ec157446e76ff
رقم الأكسشن: edsdoj.606fc10c954446a4bc8ec157446e76ff
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:17597714
17597706
DOI:10.1111/1759-7714.13966