دورية أكاديمية

Comparison of Intralesional Hyaluronic Acid vs . Verapamil for the Treatment of Acute Phase Peyronie’s Disease: A Prospective, Open-Label Non-Randomized Clinical Study

التفاصيل البيبلوغرافية
العنوان: Comparison of Intralesional Hyaluronic Acid vs . Verapamil for the Treatment of Acute Phase Peyronie’s Disease: A Prospective, Open-Label Non-Randomized Clinical Study
المؤلفون: Andrea Cocci, Fabrizio Di Maida, Gianmartin Cito, Pierangelo Verrienti, Nicola Laruccia, Riccardo Campi, Andrea Mari, Marina Di Mauro, Marco Falcone, Giovanni E. Cacciamani, Giulio Garaffa, Andrea Minervini, Giorgio Ivan Russo
المصدر: The World Journal of Men's Health, Vol 39, Iss 2, Pp 352-357 (2021)
بيانات النشر: Korean Society for Sexual Medicine and Andrology, 2021.
سنة النشر: 2021
المجموعة: LCC:Medicine
LCC:Diseases of the genitourinary system. Urology
مصطلحات موضوعية: hyaluronic acid, penile curvature, penile induration, peyronie disease, verapamil, Medicine, Diseases of the genitourinary system. Urology, RC870-923
الوصف: Purpose: To compare the efficacy and safety of intralesional hyaluronic acid (HA) as compared with verapamil injection in patients with Peyronie’s disease (PD). Materials and Methods: Between January 2015 and December 2018, men in PD acute phase were prospectively recruited. This open-label, prospective study included 2 different protocols. Group A: 8-week cycle of weekly intraplaque injections with HA; Group B: 8-week cycle of weekly intraplaque injections with verapamil. Penile curvature, plaque size, International Index of Erectile Function (IIEF)-15 score and visual analogue scale (VAS) were assessed at baseline and after 3 months. Results: Two-hundred forty-four patients were enrolled. Of these, 125 received intralesional HA (Group A), 119 received intralesional verapamil (Group B). At enrollment, median age was 56.0 years (interquartile range [IQR]=47.0–63.0 years), median curvature 35.0° (IQR=25.0°–45.0°), median IIEF-15 score 19.0 (IQR=16.0–23.0), median VAS 4.0 (IQR=4.0–5.0). Median difference for IIEF-15 was 1.0 (95% confidence interval [CI]=1.12–1.94) in Group A and 0.0 (95% CI=-0.04–0.14) in Group B (p
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2287-4208
2287-4690
Relation: https://doaj.org/toc/2287-4208; https://doaj.org/toc/2287-4690
DOI: 10.5534/wjmh.190108
URL الوصول: https://doaj.org/article/d62901c7d6a84137bb93a8ac61cb0444
رقم الأكسشن: edsdoj.62901c7d6a84137bb93a8ac61cb0444
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:22874208
22874690
DOI:10.5534/wjmh.190108