دورية أكاديمية
Comparison of Intralesional Hyaluronic Acid vs . Verapamil for the Treatment of Acute Phase Peyronie’s Disease: A Prospective, Open-Label Non-Randomized Clinical Study
العنوان: | Comparison of Intralesional Hyaluronic Acid vs . Verapamil for the Treatment of Acute Phase Peyronie’s Disease: A Prospective, Open-Label Non-Randomized Clinical Study |
---|---|
المؤلفون: | Andrea Cocci, Fabrizio Di Maida, Gianmartin Cito, Pierangelo Verrienti, Nicola Laruccia, Riccardo Campi, Andrea Mari, Marina Di Mauro, Marco Falcone, Giovanni E. Cacciamani, Giulio Garaffa, Andrea Minervini, Giorgio Ivan Russo |
المصدر: | The World Journal of Men's Health, Vol 39, Iss 2, Pp 352-357 (2021) |
بيانات النشر: | Korean Society for Sexual Medicine and Andrology, 2021. |
سنة النشر: | 2021 |
المجموعة: | LCC:Medicine LCC:Diseases of the genitourinary system. Urology |
مصطلحات موضوعية: | hyaluronic acid, penile curvature, penile induration, peyronie disease, verapamil, Medicine, Diseases of the genitourinary system. Urology, RC870-923 |
الوصف: | Purpose: To compare the efficacy and safety of intralesional hyaluronic acid (HA) as compared with verapamil injection in patients with Peyronie’s disease (PD). Materials and Methods: Between January 2015 and December 2018, men in PD acute phase were prospectively recruited. This open-label, prospective study included 2 different protocols. Group A: 8-week cycle of weekly intraplaque injections with HA; Group B: 8-week cycle of weekly intraplaque injections with verapamil. Penile curvature, plaque size, International Index of Erectile Function (IIEF)-15 score and visual analogue scale (VAS) were assessed at baseline and after 3 months. Results: Two-hundred forty-four patients were enrolled. Of these, 125 received intralesional HA (Group A), 119 received intralesional verapamil (Group B). At enrollment, median age was 56.0 years (interquartile range [IQR]=47.0–63.0 years), median curvature 35.0° (IQR=25.0°–45.0°), median IIEF-15 score 19.0 (IQR=16.0–23.0), median VAS 4.0 (IQR=4.0–5.0). Median difference for IIEF-15 was 1.0 (95% confidence interval [CI]=1.12–1.94) in Group A and 0.0 (95% CI=-0.04–0.14) in Group B (p |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 2287-4208 2287-4690 |
Relation: | https://doaj.org/toc/2287-4208; https://doaj.org/toc/2287-4690 |
DOI: | 10.5534/wjmh.190108 |
URL الوصول: | https://doaj.org/article/d62901c7d6a84137bb93a8ac61cb0444 |
رقم الأكسشن: | edsdoj.62901c7d6a84137bb93a8ac61cb0444 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 22874208 22874690 |
---|---|
DOI: | 10.5534/wjmh.190108 |