دورية أكاديمية
Adjuvant-induced autoimmune syndrome triggered by silicone breast implants: systematic review
| العنوان: | Adjuvant-induced autoimmune syndrome triggered by silicone breast implants: systematic review |
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| المؤلفون: | Caio Munaretto Giacomazzo, Caroline Noda Sakai, Rayane Merlly Gandolfi de Araujo, Maria Cecilia Closs Ono, Alfredo Benjamin Duarte-da-Silva, Renato da Silva Freitas |
| المصدر: | Revista Brasileira de Cirurgia Plástica, Vol 37, Iss 04, Pp 485-493 (2022) |
| بيانات النشر: | Sociedade Brasileira de Cirurgia Plástica, 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Surgery |
| مصطلحات موضوعية: | breast implants, silicone elastomers, adjuvants, immunologic, autoimmunity, systematic review., Surgery, RD1-811 |
| الوصف: | Adjuvant-induced autoimmune syndrome (ASIA) and its diagnostic criteria were described by Shoenfeld in 2011, relating symptoms of autoimmunity to adjuvants, such as silicone, present in breast implants. This systematic review aimed to gather data from the literature on symptomatology, incidence and proposed treatments for ASIA caused by silicone breast implants (SBI). Searches were carried out in PubMed, LILACS, Embase and Cochrane databases, using the descriptors “Autoimmune Syndrome Induced by Adjuvants,” “Breast implant,” and “Silicone Implant Incompatibility Syndrome.” The search strategy generated 95 articles, of which 20 were included in the review. The authors suggest three main theories to explain the development of the syndrome: genetic predisposition, silicone bleeding and the formation of a periprosthetic capsule. The most frequently described clinical manifestations include chronic fatigue, arthralgia, myalgia, and cognitive and sleep disorders. There is no consensus on laboratory findings and associated risk factors; recent studies propose expanding the diagnostic criteria initially described. Adequate treatment remains controversial, ranging from medications to prosthesis explantation. Although the reviewed articles suggest the existence of ASIA related to SBI, its precise pathophysiology is unknown, the symptoms reported are nonspecific, and the time between exposure and the onset of manifestations is uncertain. This systematic review concludes that, to date, there is not enough scientific evidence to establish the causality of the development of adjuvant-induced autoimmune syndrome resulting from silicone breast implants. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English Portuguese |
| تدمد: | 1983-5175 2177-1235 |
| Relation: | http://www.rbcp.org.br/export-pdf/3213/en_v37n4a15.pdf; https://doaj.org/toc/1983-5175; https://doaj.org/toc/2177-1235 |
| DOI: | 10.5935/2177-1235.2022RBCP.626-en |
| URL الوصول: | https://doaj.org/article/62c12c312b15426bb3225d0c3cdde4fd |
| رقم الأكسشن: | edsdoj.62c12c312b15426bb3225d0c3cdde4fd |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 19835175 21771235 |
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| DOI: | 10.5935/2177-1235.2022RBCP.626-en |