دورية أكاديمية
Classification of congenital cataracts based on multidimensional phenotypes and its association with visual outcomes
العنوان: | Classification of congenital cataracts based on multidimensional phenotypes and its association with visual outcomes |
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المؤلفون: | Yuan Tan, Ying-Shi Zou, Ying-Lin Yu, Le-Yi Hu, Ting Zhang, Hui Chen, Ling Jin, Duo-Ru Lin, Yi-Zhi Liu, Hao-Tian Lin, Zhen-Zhen Liu |
المصدر: | International Journal of Ophthalmology, Vol 17, Iss 3, Pp 473-479 (2024) |
بيانات النشر: | Press of International Journal of Ophthalmology (IJO PRESS), 2024. |
سنة النشر: | 2024 |
المجموعة: | LCC:Ophthalmology |
مصطلحات موضوعية: | classification, congenital cataract, phenotype, visual acuity, cluster analysis, Ophthalmology, RE1-994 |
الوصف: | AIM: To establish a classification for congenital cataracts that can facilitate individualized treatment and help identify individuals with a high likelihood of different visual outcomes. METHODS: Consecutive patients diagnosed with congenital cataracts and undergoing surgery between January 2005 and November 2021 were recruited. Data on visual outcomes and the phenotypic characteristics of ocular biometry and the anterior and posterior segments were extracted from the patients' medical records. A hierarchical cluster analysis was performed. The main outcome measure was the identification of distinct clusters of eyes with congenital cataracts. RESULTS: A total of 164 children (299 eyes) were divided into two clusters based on their ocular features. Cluster 1 (96 eyes) had a shorter axial length (mean±SD, 19.44±1.68 mm), a low prevalence of macular abnormalities (1.04%), and no retinal abnormalities or posterior cataracts. Cluster 2 (203 eyes) had a greater axial length (mean±SD, 20.42±2.10 mm) and a higher prevalence of macular abnormalities (8.37%), retinal abnormalities (98.52%), and posterior cataracts (4.93%). Compared with the eyes in Cluster 2 (57.14%), those in Cluster 1 (71.88%) had a 2.2 times higher chance of good best-corrected visual acuity [ |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 2222-3959 2227-4898 |
Relation: | http://ies.ijo.cn/en_publish/2024/3/20240308.pdf; https://doaj.org/toc/2222-3959; https://doaj.org/toc/2227-4898 |
DOI: | 10.18240/ijo.2024.03.08 |
URL الوصول: | https://doaj.org/article/62ee7c7b8ac142d6b0f7b46dca49ebf4 |
رقم الأكسشن: | edsdoj.62ee7c7b8ac142d6b0f7b46dca49ebf4 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 22223959 22274898 |
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DOI: | 10.18240/ijo.2024.03.08 |