Dynamic disorganization of synaptic NMDA receptors triggered by autoantibodies from psychotic patients

التفاصيل البيبلوغرافية
العنوان:	Dynamic disorganization of synaptic NMDA receptors triggered by autoantibodies from psychotic patients
المؤلفون:	Julie Jézéquel, Emily M. Johansson, Julien P. Dupuis, Véronique Rogemond, Hélène Gréa, Blanka Kellermayer, Nora Hamdani, Emmanuel Le Guen, Corentin Rabu, Marilyn Lepleux, Marianna Spatola, Elodie Mathias, Delphine Bouchet, Amy J. Ramsey, Robert H. Yolken, Ryad Tamouza, Josep Dalmau, Jérôme Honnorat, Marion Leboyer, Laurent Groc
المصدر:	Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
بيانات النشر:	Nature Portfolio, 2017.
سنة النشر:	2017
المجموعة:	LCC:Science
مصطلحات موضوعية:	Science
الوصف:	Autoantibodies are found in neuropsychiatric conditions but without clear cellular mechanism and disease relevance. This study shows higher prevalence of autoantibodies against NMDAR receptors in schizophrenia patients, and patient-associated antibody can alter synaptic receptor trafficking and plasticity.
نوع الوثيقة:	article
وصف الملف:	electronic resource
اللغة:	English
تدمد:	2041-1723
Relation:	https://doaj.org/toc/2041-1723
DOI:	10.1038/s41467-017-01700-3
URL الوصول:	https://doaj.org/article/641d0c18165948329f6f6c33b654b354
رقم الأكسشن:	edsdoj.641d0c18165948329f6f6c33b654b354
قاعدة البيانات:	Directory of Open Access Journals

الوصف
تدمد:	20411723
DOI:	10.1038/s41467-017-01700-3