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Visualization of coronary wall atherosclerosis in asymptomatic subjects and patients with coronary artery disease using magnetic resonance imaging.

التفاصيل البيبلوغرافية
العنوان: Visualization of coronary wall atherosclerosis in asymptomatic subjects and patients with coronary artery disease using magnetic resonance imaging.
المؤلفون: Suzanne C Gerretsen, M Eline Kooi, Alfons G Kessels, Simon Schalla, Marcus Katoh, Rob J van der Geest, Warren J Manning, Johannes Waltenberger, Jos M A van Engelshoven, Rene M Botnar, Tim Leiner
المصدر: PLoS ONE, Vol 5, Iss 9 (2010)
بيانات النشر: Public Library of Science (PLoS), 2010.
سنة النشر: 2010
المجموعة: LCC:Medicine
LCC:Science
مصطلحات موضوعية: Medicine, Science
الوصف: Magnetic resonance imaging (MRI) is sensitive to early atherosclerotic changes such as positive remodeling in patients with coronary artery disease (CAD). We assessed prevalence, quality, and extent of coronary atherosclerosis in a group of healthy subjects compared to patients with confirmed CAD.Twenty-two patients with confirmed CAD (15M, 7F, mean age 60.4 ± 10.4 years) and 26 healthy subjects without history of CAD (11M, 15F, mean age 56.1 ± 4.4 years) underwent MRI of the right coronary artery (RCA) and vessel wall (MR-CVW) on a clinical 1.5T MR-scanner. Wall thickness measurements of both groups were compared.Stenoses of the RCA (both < and ≥50% on CAG) were present in all patients. In 21/22 patients, stenoses detected at MRI corresponded to stenoses detected with conventional angiography. In 19/26 asymptomatic subjects, there was visible luminal narrowing in the MR luminography images. Fourteen of these subjects demonstrated corresponding increase in vessel wall thickness. In 4/26 asymptomatic subjects, vessel wall thickening without luminal narrowing was present. Maximum and mean wall thicknesses in patients were significantly higher (2.16 vs 1.92 mm, and 1.38 vs 1.22 mm, both p
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1932-6203
Relation: http://europepmc.org/articles/PMC2947500?pdf=render; https://doaj.org/toc/1932-6203
DOI: 10.1371/journal.pone.0012998
URL الوصول: https://doaj.org/article/e65da79bd8af4ab7b8f10bc404ad90b6
رقم الأكسشن: edsdoj.65da79bd8af4ab7b8f10bc404ad90b6
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:19326203
DOI:10.1371/journal.pone.0012998