دورية أكاديمية
Childhood socioeconomic status and childhood maltreatment: Distinct associations with brain structure.
| العنوان: | Childhood socioeconomic status and childhood maltreatment: Distinct associations with brain structure. |
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| المؤلفون: | Gwendolyn M Lawson, Joshua S Camins, Laura Wisse, Jue Wu, Jeffrey T Duda, Philip A Cook, James C Gee, Martha J Farah |
| المصدر: | PLoS ONE, Vol 12, Iss 4, p e0175690 (2017) |
| بيانات النشر: | Public Library of Science (PLoS), 2017. |
| سنة النشر: | 2017 |
| المجموعة: | LCC:Medicine LCC:Science |
| مصطلحات موضوعية: | Medicine, Science |
| الوصف: | The present study examined the relationship between childhood socioeconomic status (SES), childhood maltreatment, and the volumes of the hippocampus and amygdala between the ages of 25 and 36 years. Previous work has linked both low SES and maltreatment with reduced hippocampal volume in childhood, an effect attributed to childhood stress. In 46 adult subjects, only childhood maltreatment, and not childhood SES, predicted hippocampal volume in regression analyses, with greater maltreatment associated with lower volume. Neither factor was related to amygdala volume. When current SES and recent interpersonal stressful events were also considered, recent interpersonal stressful events predicted smaller hippocampal volumes over and above childhood maltreatment. Finally, exploratory analyses revealed a significant sex by childhood SES interaction, with women's childhood SES showing a significantly more positive relation (less negative) with hippocampus volume than men's. The overall effect of childhood maltreatment but not SES, and the sex-specific effect of childhood SES, indicate that different forms of stressful childhood adversity affect brain development differently. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1932-6203 |
| Relation: | http://europepmc.org/articles/PMC5393603?pdf=render; https://doaj.org/toc/1932-6203 |
| DOI: | 10.1371/journal.pone.0175690 |
| URL الوصول: | https://doaj.org/article/665b53a1d6e342ac8688ea56f5add558 |
| رقم الأكسشن: | edsdoj.665b53a1d6e342ac8688ea56f5add558 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 19326203 |
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| DOI: | 10.1371/journal.pone.0175690 |