دورية أكاديمية
أعرض في EDS

Evaluation of PSA-age volume score in predicting prostate cancer in Chinese population

التفاصيل البيبلوغرافية
العنوان: Evaluation of PSA-age volume score in predicting prostate cancer in Chinese population
المؤلفون: Yi-Shuo Wu, Xiao-Bo Wu, Ning Zhang, Guang-Liang Jiang, Yang Yu, Shi-Jun Tong, Hao-Wen Jiang, Shan-Hua Mao, Rong Na, Qiang Ding
المصدر: Asian Journal of Andrology, Vol 20, Iss 4, Pp 324-329 (2018)
بيانات النشر: Wolters Kluwer Medknow Publications, 2018.
سنة النشر: 2018
المجموعة: LCC:Diseases of the genitourinary system. Urology
مصطلحات موضوعية: age, China, prostate cancer, prostate-specific antigen, volume, Diseases of the genitourinary system. Urology, RC870-923
الوصف: This study was performed to evaluate prostate-specific antigen-age volume (PSA-AV) scores in predicting prostate cancer (PCa) in a Chinese biopsy population. A total of 2355 men who underwent initial prostate biopsy from January 2006 to November 2015 in Huashan Hospital were recruited in the current study. The PSA-AV scores were calculated and assessed together with PSA and PSA density (PSAD) retrospectively. Among 2133 patients included in the analysis, 947 (44.4%) were diagnosed with PCa. The mean age, PSA, and positive rates of digital rectal examination result and transrectal ultrasound result were statistically higher in men diagnosed with PCa (all P < 0.05). The values of area under the receiver operating characteristic curves (AUCs) of PSAD and PSA-AV were 0.864 and 0.851, respectively, in predicting PCa in the entire population, both performed better than PSA (AUC = 0.805; P < 0.05). The superiority of PSAD and PSA-AV was more obvious in subgroup with PSA ranging from 2.0 ng ml−1 to 20.0 ng ml−1. A PSA-AV score of 400 had a sensitivity and specificity of 93.7% and 40.0%, respectively. In conclusion, the PSA-AV score performed equally with PSAD and was better than PSA in predicting PCa. This indicated that PSA-AV score could be a useful tool for predicting PCa in Chinese population.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1008-682X
1745-7262
67165117
Relation: http://www.ajandrology.com/article.asp?issn=1008-682X;year=2018;volume=20;issue=4;spage=324;epage=329;aulast=Wu; https://doaj.org/toc/1008-682X; https://doaj.org/toc/1745-7262
DOI: 10.4103/aja.aja_81_17
URL الوصول: https://doaj.org/article/6716511761da48de84583df309601e98
رقم الأكسشن: edsdoj.6716511761da48de84583df309601e98
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:1008682X
17457262
67165117
DOI:10.4103/aja.aja_81_17