دورية أكاديمية
Discovering Genomic Regions Associated with Reproductive Traits and Frame Score in Mexican Simmental and Simbrah Cattle Using Individual SNP and Haplotype Markers
| العنوان: | Discovering Genomic Regions Associated with Reproductive Traits and Frame Score in Mexican Simmental and Simbrah Cattle Using Individual SNP and Haplotype Markers |
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| المؤلفون: | René Calderón-Chagoya, Vicente Eliezer Vega-Murillo, Adriana García-Ruiz, Ángel Ríos-Utrera, Guillermo Martínez-Velázquez, Moisés Montaño-Bermúdez |
| المصدر: | Genes, Vol 14, Iss 11, p 2004 (2023) |
| بيانات النشر: | MDPI AG, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Genetics |
| مصطلحات موضوعية: | genes, genome-wide association study (GWAS), haplotypes, Simbrah, Simmental, single nucleotide polymorphism (SNP), Genetics, QH426-470 |
| الوصف: | Reproductive efficiency stands as a critical determinant of profitability within beef production systems. The incorporation of molecular markers can expedite advancements in reproductive performance. While the use of SNPs in association analysis is prevalent, approaches centered on haplotypes can offer a more comprehensive insight. The study used registered Simmental and Simbrah cattle genotyped with the GGP Bovine 150 k panel. Phenotypes included scrotal circumference (SC), heifer fertility (HF), stayability (STAY), and frame score (FS). After quality control, 105,129 autosomal SNPs from 967 animals were used. Haplotype blocks were defined based on linkage disequilibrium. Comparison between haplotypes and SNPs for reproductive traits and FS was conducted using Bayesian and frequentist models. 23, 13, 7, and 2 SNPs exhibited associations with FS, SC, HF, and STAY, respectively. In addition, seven, eight, seven, and one haplotypes displayed associations with FS, SC, HF, and STAY, respectively. Within these delineated genomic segments, potential candidate genes were associated. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2073-4425 |
| Relation: | https://www.mdpi.com/2073-4425/14/11/2004; https://doaj.org/toc/2073-4425 |
| DOI: | 10.3390/genes14112004 |
| URL الوصول: | https://doaj.org/article/68309a8a950649a39a15ee64c0d7359c |
| رقم الأكسشن: | edsdoj.68309a8a950649a39a15ee64c0d7359c |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 20734425 |
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| DOI: | 10.3390/genes14112004 |