دورية أكاديمية
Negative effects of long-term feeding of high-grain diets to lactating goats on milk fat production and composition by regulating gene expression and DNA methylation in the mammary gland
| العنوان: | Negative effects of long-term feeding of high-grain diets to lactating goats on milk fat production and composition by regulating gene expression and DNA methylation in the mammary gland |
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| المؤلفون: | Ping Tian, Yanwen Luo, Xian Li, Jing Tian, Shiyu Tao, Canfeng Hua, Yali Geng, Yingdong Ni, Ruqian Zhao |
| المصدر: | Journal of Animal Science and Biotechnology, Vol 8, Iss 1, Pp 1-11 (2017) |
| بيانات النشر: | BMC, 2017. |
| سنة النشر: | 2017 |
| المجموعة: | LCC:Animal culture LCC:Veterinary medicine |
| مصطلحات موضوعية: | DNA methylation, Gene expression, Goat, High concentrate diet, Milk fat, Animal culture, SF1-1100, Veterinary medicine, SF600-1100 |
| الوصف: | Abstract Background It is well known that feeding a high concentrate (HC) diet to lactating ruminants likely induces subacute ruminal acidosis (SARA) and leads to a decrease in milk fat production. However, the effects of feeding a HC diet for long periods on milk fatty acids composition and the mechanism behind the decline of milk fat still remains poorly understood. The aim of this study was to investigate the impact of feeding a HC diet to lactating dairy goats on milk fat yield and fatty acids composition with an emphasis on the mechanisms underlying the milk fat depression. Seventeen mid-lactating dairy goats were randomly allocated to three groups. The control treatment was fed a low-concentrate diet (35% concentrate, n = 5, LC) and there were two high-concentrate treatments (65% concentrate, HC), one fed a high concentrate diet for a long period (19 wks, n = 7, HL); one fed a high concentrate diet for a short period of time (4 wk, n = 5, HS). Milk fat production and fatty acids profiles were measured. In order to investigate the mechanisms underlying the changes in milk fat production and composition, the gene expression involved in lipid metabolism and DNA methylation in the mammary gland were also analyzed. Results Milk production was increased by feeding the HC diet in the HS and HL groups compared with the LC diet (P |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2049-1891 |
| Relation: | http://link.springer.com/article/10.1186/s40104-017-0204-2; https://doaj.org/toc/2049-1891 |
| DOI: | 10.1186/s40104-017-0204-2 |
| URL الوصول: | https://doaj.org/article/68a2df4fc8e44e6bb53a6c40baf03b0e |
| رقم الأكسشن: | edsdoj.68a2df4fc8e44e6bb53a6c40baf03b0e |
| قاعدة البيانات: | Directory of Open Access Journals |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 20491891 |
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| DOI: | 10.1186/s40104-017-0204-2 |