دورية أكاديمية

DNA Expression Profi les of Non-Small Cell Lung Cancer

التفاصيل البيبلوغرافية
العنوان: DNA Expression Profi les of Non-Small Cell Lung Cancer
المؤلفون: Joseph Siu-Kie AU, William Chi-Shing CHO, Sheung-Chun CHOW, Mengsu YANG
المصدر: Chinese Journal of Lung Cancer, Vol 12, Iss 1, Pp 8-15 (2009)
بيانات النشر: Chinese Anti-Cancer Association; Chinese Antituberculosis Association, 2009.
سنة النشر: 2009
المجموعة: LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens
مصطلحات موضوعية: Microarray, DNA expression profi ling, Lung neoplasms, Biomarkers, Epidermal growth factor receptor (EGFR) mutation, Smoking, Personalized medicine, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
الوصف: DNA expression profi ling using microarray technology has been applied to studies on the molecular classifi cation of lung cancers, pathogenetic alterations in gene expressions and cellular pathways,prediction of prognosis and metastasis, customized therapies, and drug development. Due to the wide variation in technical factors, different cohorts of patients and biological heterogeneity, the major hurdle to successful clinical application is lack of robustness, reliability and reproducibility of data. With betterstandardization and better analytic approaches to cut down the noises from the high dimensionality of data,microarray technologies may be ready to make its way to the doctor's offi ce with contribution to personalized treatment of lung cancer in the future.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: Chinese
تدمد: 1009-3419
1999-6187
Relation: http://www.lungca.org/index.php?journal=01&page=article&op=view&path%5B%5D=10.3779%2Fj.issn.1009-3419.2009.01.002&path%5B%5D=194; https://doaj.org/toc/1009-3419; https://doaj.org/toc/1999-6187
URL الوصول: https://doaj.org/article/692e02dc11814104ad835889daec1e14
رقم الأكسشن: edsdoj.692e02dc11814104ad835889daec1e14
قاعدة البيانات: Directory of Open Access Journals