دورية أكاديمية
Effect of transcutaneous electrical acupoint stimulation on postoperative cognitive function in older patients with lung cancer: A randomized, double-blind, placebo-controlled trial
العنوان: | Effect of transcutaneous electrical acupoint stimulation on postoperative cognitive function in older patients with lung cancer: A randomized, double-blind, placebo-controlled trial |
---|---|
المؤلفون: | Fei Guo, Ruili Han, Li Sun, Lanlan Zheng, Yanzheng Wang, Yuting Yan, Chen Liu, Yuan Qin, Chen Yuan, Shuang Wang, Xude Sun, Changjun Gao |
المصدر: | Heliyon, Vol 9, Iss 9, Pp e19386- (2023) |
بيانات النشر: | Elsevier, 2023. |
سنة النشر: | 2023 |
المجموعة: | LCC:Science (General) LCC:Social sciences (General) |
مصطلحات موضوعية: | Transcutaneous electrical acupoint stimulation(TEAS), Postoperative cognitive dysfunction(POCD), Quality of life, Lung cancer, Older patients, Science (General), Q1-390, Social sciences (General), H1-99 |
الوصف: | Objective: This trial was to examine the effect of transcutaneous electrical acupoint stimulation (TEAS) on postoperative cognitive function in older patients who underwent thoracoscopic pulmonary resection. Methods: This was a prospective, randomized, double-blind, placebo-controlled study. 128 patients scheduled for surgery were randomly assigned to the TEAS group and sham-TEAS group. A standardized intervention of TEAS or sham-TEAS on the acupoints of Baihui (DU20) and bilateral Neiguan (PC6), Hegu (LI4), and Zusanli (ST36) from 30 min before anesthesia induction until the end of the surgery, combined with a general anesthetic protocol performed in the two groups respectively. The primary outcome was the incidence of postoperative cognitive dysfunction (POCD) assessed via the Montreal Cognitive Assessment (MoCA) scale at each time point. The secondary outcomes included the results of the Mini-Mental State Examination (MMSE) score, the Numerical Rating Scale (NRS) on pain and sleep, the European Organization for Research and Treatment of Cancer Quality of Life (EORTC-QLQ-C30), and a chronic pain questionnaire at relative time points. Results: Participants who completed the 12-month trial of the two groups were well-matched in baseline demographic and clinical parameters. At postoperative day 1, day 7, and day 30 time points, the incidence of POCD in the sham-TEAS group was always significantly higher than in the TEAS group (65.4% vs 20%, 43.6% vs 7.3%, 40% vs 3.6%, all P |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 2405-8440 |
Relation: | http://www.sciencedirect.com/science/article/pii/S2405844023065945; https://doaj.org/toc/2405-8440 |
DOI: | 10.1016/j.heliyon.2023.e19386 |
URL الوصول: | https://doaj.org/article/695591d14cb54fc8b957c04c9154f837 |
رقم الأكسشن: | edsdoj.695591d14cb54fc8b957c04c9154f837 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 24058440 |
---|---|
DOI: | 10.1016/j.heliyon.2023.e19386 |