Amare Desalegn Wolide,1 Belay Zawdie,2 Tilahun Alemayehu,3 Samuel Tadesse1 1Department of Medical Physiology, 2Department of Medical Biochemistry, 3Department of Human Anatomy, College of Health Sciences, Jimma University, Jimma, Ethiopia Background: The chronic hyperglycemia of diabetes has been associated with an imbalance of some trace metal elements in the blood sample of type 2 diabetes patients. Aim: To evaluate the status of serum ferritin and some selected metal elements among type 2 diabetes mellitus (T2DM) patients. Methods: Facility-based comparative cross-sectional study was conducted from February 15, 2015 to October 30, 2015, at Jimma University Specialized Hospital, Ethiopia. A total of 428 type 2 diabetes and nondiabetes study subjects were recruited to the study. After overnight fasting, 10 mL of venous blood samples were taken for biochemical and trace metal element analysis. Data were entered into EpiData version 3.5.1 and exported to SPSS version 20 for Windows for analysis. Results: Serum concentration of Zn+2, Mg+2, Cr+3, ferritin, and Fe+3 in patients with type 2 diabetes was significantly lower (p
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